Lyons B M, Donald P J
Skull Base Surg. 1992;2(2):87-91. doi: 10.1055/s-2008-1057116.
Juvenile angiofibroma is a benign tumor, well known for aggressive extracranial growth, that frequently spreads to involve the skull base and intracranial compartment as well. The meninges, however, provide a strong barrier against intracerebral spread. This article reports an unusual case of angiofibroma with dural penetration, cavernous sinus involvement, and adherence to the temporal lobe of the brain. Controversy exists as to how the intracranial extensions are best managed. Our experience with this case, combined with review of the literature, suggests that these lesions can be removed surgically, eliminating in most cases the need for radiation therapy.
青少年血管纤维瘤是一种良性肿瘤,以颅外侵袭性生长而闻名,常扩散至累及颅底及颅内腔室。然而,脑膜对脑内扩散形成了强大的屏障。本文报告了一例罕见的血管纤维瘤病例,该肿瘤穿透硬脑膜,累及海绵窦并附着于脑颞叶。对于颅内扩展病变的最佳处理方式存在争议。我们对该病例的经验结合文献回顾表明,这些病变可通过手术切除,多数情况下无需进行放射治疗。