Amirzargar Mohammad Ali, Yavangi Mahnaz, Ghorbanpour Manouchehr, Hosseini Moghaddam Seyed Mohammadmehdi, Rahnavardi Mohammad, Amirzargar Nasibeh
Department of Urology, Ekbatan Hospital, Hamadan University of Medical Sciences, Hamadan, Iran.
Int Urol Nephrol. 2007;39(3):779-85. doi: 10.1007/s11255-006-9143-0. Epub 2006 Dec 14.
We aimed to describe our experience in administering an innovative surgical technique to treat pediatric cases of exstrophy-epispadias complex.
Between 1995 and 2004, seven consecutive patients (six males) with exstrophy-epispadias complex were treated using ileocecal segment for bladder augmentation and appendix for urethral reconstruction. In a single-stage operation, the exstrophied bladder was dissected- and a segment of cecum, ascending colon, terminal ileum, and the corresponding appendix were isolated. Using the opened colon to augment the bladder, the ileal segment was fashioned to skin as temporary stoma, and the appendix was laid in the urethral lumen as the neourethra following urethral demucosation. This technique was used as a secondary surgery in one case and as a primary surgery in six neonates. Evaluation of the urinary tract status was performed by cystograms and ultrasonograms.
Renal function was saved in all cases and continence was achieved by clean intermittent catheterization every two hours either via the neourethra (n = 6) or through the temporary stoma (n = 1). The patients did not experience any metabolic complications in their follow-ups. Moreover, no one had vesicourethral reflux, dehiscence, or fistula.
The technique was deemed safe with acceptable outcomes even when secondary repair of previously failed operation was intended. Experiencing the technique in larger cohorts as well as longer follow-ups might be necessary to assess probable long-term complications.
我们旨在描述运用一种创新手术技术治疗小儿膀胱外翻-尿道上裂综合征病例的经验。
1995年至2004年期间,连续7例(6例男性)膀胱外翻-尿道上裂综合征患者采用回盲肠段进行膀胱扩大术,并采用阑尾进行尿道重建术。在一期手术中,解剖外翻的膀胱,分离一段盲肠、升结肠、回肠末端及相应的阑尾。利用开放的结肠扩大膀胱,将回肠段制成皮肤临时造口,在尿道黏膜剥脱后将阑尾置于尿道腔内作为新尿道。该技术在1例患者中作为二期手术使用,在6例新生儿中作为一期手术使用。通过膀胱造影和超声检查评估尿路状况。
所有病例均保留了肾功能,6例通过新尿道、1例通过临时造口每两小时进行一次清洁间歇性导尿实现了控尿。患者在随访期间未出现任何代谢并发症。此外,无一例发生膀胱输尿管反流、裂开或瘘管。
即使是对先前失败手术进行二期修复,该技术也被认为是安全的,且效果可接受。可能需要在更大的队列中应用该技术并进行更长时间的随访,以评估可能的长期并发症。