DeCambre Marvalyn, Casale Pasquale, Grady Richard, Swartz Mia, Mitchell Michael
Center for Genomics and Healthcare Equality, University of Washington School of Medicine, Seattle, WA, USA.
J Urol. 2006 Jul;176(1):288-91. doi: 10.1016/S0022-5347(06)00583-0.
Reconstruction of the urethra without adequate circumferential muscular support is a significant problem in bladder neck surgery for urinary incontinence. Fascial, muscular and artificial slings have been used for support of the bladder neck after reconstruction. We used a demucosalized detrusor muscle pedicle to wrap around the bladder neck base along with other continence techniques in children who experienced incontinence after staged closure of exstrophy and epispadias. We describe our experience using the pedicle wraparound along with the Mitchell modification of Young-Dees-Leadbetter bladder neck reconstruction.
We reviewed our continence rates using a detrusor wraparound in 8 eligible patients with failed staged exstrophy-epispadias repair. We defined incontinence as any degree of leakage through the bladder neck day or night.
Of the 8 patients studied 2 were female and 6 were male. Mean patient age at surgery was 7.6 years (range 4 to 11). Mean followup was 3.2 years (range 0.5 to 5). All patients with staged exstrophy-epispadias repair failure are currently continent. Five patients underwent simultaneous bladder augmentation. All but 2 patients catheterize via a Mitrofanoff channel. Three patients void volitionally and 5 use clean intermittent catheterization per Mitrofanoff. Two patients required dextranomer/hyaluronic acid injections at the bladder neck postoperatively to achieve complete dryness.
The detrusor bladder neck wraparound, while successful, may require concomitant surgery, including augmentation, clean intermittent catheterization and endoscopic injection therapy, to achieve continence following failure of staged exstrophy-epispadias repair. The detrusor bladder neck wrap appears to be a safe and effective adjunctive procedure in this patient population. We believe it has an important role in the achievement of urinary dryness.
在膀胱颈手术治疗尿失禁时,重建尿道而没有足够的环形肌肉支撑是一个重大问题。筋膜、肌肉和人工吊带已被用于重建后支撑膀胱颈。我们在分期关闭膀胱外翻和尿道上裂后出现尿失禁的儿童中,使用去黏膜化逼尿肌肌蒂包裹膀胱颈基部,并结合其他控尿技术。我们描述了使用肌蒂包裹术以及对Young-Dees-Leadbetter膀胱颈重建术进行米切尔改良的经验。
我们回顾了8例分期膀胱外翻-尿道上裂修复失败的合格患者使用逼尿肌包裹术的控尿率。我们将尿失禁定义为膀胱颈白天或夜间有任何程度的漏尿。
在研究的8例患者中,2例为女性,6例为男性。手术时患者的平均年龄为7.6岁(范围4至11岁)。平均随访时间为3.2年(范围0.5至5年)。所有分期膀胱外翻-尿道上裂修复失败的患者目前均能控尿。5例患者同时进行了膀胱扩大术。除2例患者外,所有患者均通过米氏通道进行导尿。3例患者能自主排尿,5例通过米氏通道进行清洁间歇性导尿。2例患者术后需要在膀胱颈注射葡聚糖/透明质酸以达到完全干爽。
逼尿肌膀胱颈包裹术虽然成功,但可能需要同时进行包括扩大术、清洁间歇性导尿和内镜注射治疗在内的手术,以在分期膀胱外翻-尿道上裂修复失败后实现控尿。逼尿肌膀胱颈包裹术在该患者群体中似乎是一种安全有效的辅助手术。我们认为它在实现尿液干爽方面具有重要作用。