一种用于控制移植自体颌下唾液腺治疗干眼症时过度分泌的新技术。
Novel technique to control hypersecretion from a transplanted autologous submandibular salivary gland for keratoconjunctivitis sicca.
作者信息
Leibovitch Igal, Hoyama Erika, Limawararut Vanessa, Crompton John, Selva Dinesh
机构信息
Oculoplastic and Orbital Unit, Department of Ophthalmology and Visual Sciences, University of Adelaide, South Australia, Australia.
出版信息
Cornea. 2006 Dec;25(10):1251-3. doi: 10.1097/01.ico.0000225718.93006.44.
PURPOSE
To present a novel technique to control hypersecretion from a transplanted autologous submandibular gland (SMG) in a patient with keratoconjunctivitis sicca.
METHODS
A 65-year-old man presented with corneal epithelial edema and suspicious ocular surface dysplasia secondary to hypersecretion from a transplanted autologous SMG. The location and function of the gland were evaluated perioperatively using technetium-99m-pertechnetate scintigraphy. The course of the duct was marked with a radiation probe, surgically exposed, and partially ligated with titanium clips.
RESULTS
Marked reduction in salivary flow and resolution of corneal edema and ocular surface changes were noted. Conjunctival biopsy showed no evidence of malignancy. Symptoms were stable during a 1-year follow-up period.
CONCLUSION
Partial ligation of the transplanted SMG duct may be a simple and reversible technique to control hypersecreting glands with secondary corneal edema and ocular surface changes.
目的
介绍一种用于控制干燥性角结膜炎患者移植的自体颌下腺（SMG）分泌亢进的新技术。
方法
一名65岁男性因移植的自体SMG分泌亢进继发角膜上皮水肿和可疑的眼表发育异常前来就诊。术中使用99m锝-高锝酸盐闪烁显像评估腺体的位置和功能。用放射性探头标记导管走行，手术暴露后用钛夹部分结扎。
结果
唾液分泌明显减少，角膜水肿和眼表改变消退。结膜活检未发现恶性证据。在1年的随访期内症状稳定。
结论
移植的SMG导管部分结扎可能是一种简单且可逆的技术，用于控制伴有继发性角膜水肿和眼表改变的分泌亢进腺体。
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