Vichnin Michelle, Freeman Ellen W, Lin Hui, Hillman Janice, Bui Stephanie
Departments of Obstetrics/Gynecology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
J Pediatr Adolesc Gynecol. 2006 Dec;19(6):397-402. doi: 10.1016/j.jpag.2006.06.015.
Identify the presence of patients with premenstrual syndrome (PMS) in an adolescent gynecology practice, and evaluate the reported severity, impairment and timing of the symptoms in the menstrual cycle.
Adolescents ages 13-18 years completed a symptom questionnaire, functional impairment ratings, and a brief medical history questionnaire during an office visit. Teens who responded that they had PMS and reported a premenstrual symptom score at least 50% greater than the postmenstrual score and rated moderate to severe impairment in one or more domains comprised the "PMS" group. Teens who responded that they had PMS but did not meet the symptom and impairment criteria were termed "PMS not supported." Teens who responded that they did not have PMS and did not meet the PMS symptom and impairment criteria were termed "No PMS."
Study participants (n = 94) had a mean age of 16.5 years (+/-1.3 SD); 31% met the criteria for the PMS group, 54% said they had PMS but did not meet criteria, and 15% clearly had no PMS. In the PMS group, the most severe symptoms were mood swings, anxiety, and irritability, with the greatest impairment in the home/family domain. Dysmenorrhea and the duration of PMS were significantly associated (P < 0.01) with PMS in univariate and multivariate analyses.
The reports of premenstrual symptoms, their severity, timing and impairment suggest that PMS is common in adolescents. Further study is warranted to confirm these results with prospective assessment of PMS and to evaluate treatments for adolescents who have clinically significant PMS.
在青少年妇科门诊中识别经前综合征(PMS)患者的存在情况,并评估所报告症状在月经周期中的严重程度、功能损害及出现时间。
13 - 18岁的青少年在门诊就诊时完成一份症状问卷、功能损害评分及一份简要病史问卷。那些回答自己患有PMS且报告经前症状评分比经后评分至少高50%,并在一个或多个领域评定为中度至重度功能损害的青少年组成“PMS”组。那些回答自己患有PMS但未达到症状及功能损害标准的青少年被称为“PMS未获支持”组。那些回答自己没有PMS且未达到PMS症状及功能损害标准的青少年被称为“无PMS”组。
研究参与者(n = 94)的平均年龄为16.5岁(±1.3标准差);31%符合PMS组标准,54%称自己患有PMS但未达标准,15%明确无PMS。在PMS组中,最严重的症状是情绪波动、焦虑和易怒,在家庭/家人领域功能损害最大。痛经及PMS持续时间在单因素和多因素分析中均与PMS显著相关(P < 0.01)。
经前症状的报告、其严重程度、出现时间及功能损害表明PMS在青少年中很常见。有必要进行进一步研究,通过对PMS的前瞻性评估来证实这些结果,并评估对有临床显著PMS的青少年的治疗方法。