Reviriego Felipe, Rodríguez-Franco Maria Isabel, Navarro Pilar, García-España Enrique, Liu-Gonzalez Malva, Verdejo Begoña, Domènech Antonio
Instituto de Química Médica, Centro de Química Orgánica Manuel Lora Tamayo, CSIC, Juan de la Cierva 3, 28006 Madrid, Spain.
J Am Chem Soc. 2006 Dec 27;128(51):16458-9. doi: 10.1021/ja064657h.
The sodium salt of the diethyl 1H-pyrazole-3,5-dicarboxylate (2) of amphiphilic character is able to interact with (+)-amphetamine, (+)-methamphetamine, and dopamine, yielding stable complexes. Crystal structure of 2 with (+)-amphetamine leads to a very nice double helical supramolecular structure.