度洛西汀商业样品中一种酚类杂质的分离与表征
Isolation and characterisation of a phenolic impurity in a commercial sample of duloxetine.
作者信息
Brenna Elisabetta, Frigoli Samuele, Fronza Giovanni, Fuganti Claudio, Malpezzi Luciana
机构信息
Dipartimento di Chimica, Materiali, Ingegneria Chimica, Politecnico di Milano, ed Istituto CNR per la Chimica del Riconoscimento Molecolare, Via Mancinelli 7, I-20131 Milano, Italy.
出版信息
J Pharm Biomed Anal. 2007 Mar 12;43(4):1573-5. doi: 10.1016/j.jpba.2006.11.026. Epub 2006 Dec 18.
PMID:17178448
Abstract
A phenolic impurity of duloxetine hydrochloride was isolated and characterised (MS, NMR, X-ray-analysis).
摘要
分离并表征了盐酸度洛西汀的一种酚类杂质（质谱、核磁共振、X射线分析）。
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