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达泊西汀作为一种性保健品中的掺杂物的分离和结构解析，用于增强性表现。

Isolation and structural elucidation of dapoxetine as an adulterant in a health supplement used for sexual performance enhancement.

机构信息

Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore.

出版信息

J Pharm Biomed Anal. 2009 Dec 5;50(5):724-8. doi: 10.1016/j.jpba.2009.06.005. Epub 2009 Jun 12.

DOI:10.1016/j.jpba.2009.06.005
PMID:19574010
Abstract

A health supplement used for sexual performance enhancement was sent to Health Sciences Authority of Singapore for testing. An unknown compound was detected and isolated and its structure was elucidated using NMR, high-resolution MS, ESI-MS/MS, UV and IR. The compound, dapoxetine, is reported to be a selective serotonin reuptake inhibitor under investigation for the treatment of premature ejaculation.

摘要

一种用于增强性功能的保健品被送往新加坡卫生科学局进行检测。检测到一种未知化合物并将其分离，使用 NMR、高分辨率 MS、ESI-MS/MS、UV 和 IR 对其结构进行了阐明。该化合物达泊西汀被报道为一种选择性 5-羟色胺再摄取抑制剂，正在研究用于治疗早泄。

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