Tang F, Man W S
Department of Physiology, Faculty of Medicine, University of Hong Kong.
Neuropeptides. 1991 Aug;19(4):287-92. doi: 10.1016/0143-4179(91)90096-2.
There was no apparent difference in the regional distribution of neuropeptides in the brain of male and female rats. The highest levels of immunoreactive leu-enkephalin, TRH, substance P and somatostatin were found in the hypothalamus, while the striatum and the cerebral cortex had the highest concentrations of met-enkephalin and cholecystokinin respectively. The lowest concentrations of these were found in the cerebellum. Enkephalins (cerebral cortex), substance P (cerebral cortex and brain stem), and somatostatin (brain stem and striatum) showed higher level in the female while enkephalin and substance P contents in the anterior pituitary were higher in the male.
雄性和雌性大鼠大脑中神经肽的区域分布没有明显差异。免疫反应性亮氨酸脑啡肽、促甲状腺激素释放激素、P物质和生长抑素的最高水平出现在下丘脑，而纹状体和大脑皮层分别具有最高浓度的甲硫氨酸脑啡肽和胆囊收缩素。这些物质在小脑中的浓度最低。脑啡肽（大脑皮层）、P物质（大脑皮层和脑干）和生长抑素（脑干和纹状体）在雌性中水平较高，而垂体前叶中脑啡肽和P物质的含量在雄性中较高。
