Agrawal Anshu, Agrawal Sudhanshu, Gupta Sudhir
Division of Basic and Clinical Immunology, University of California, Irvine, CA 92697, United States.
Exp Gerontol. 2007 May;42(5):421-6. doi: 10.1016/j.exger.2006.11.007. Epub 2006 Dec 19.
Dendritic cells (DCs) play a critical role in linking innate and adaptive immunity. A role of DCs in immunosenescence and chronic inflammation associated with aging has not been investigated in detail. In this article, we will briefly review DCs biology and changes associated with human aging.
树突状细胞(DCs)在连接先天性免疫和适应性免疫方面发挥着关键作用。DCs在与衰老相关的免疫衰老和慢性炎症中的作用尚未得到详细研究。在本文中,我们将简要回顾DCs的生物学特性以及与人类衰老相关的变化。