衰老过程中树突状细胞的生物学特性
Biology of dendritic cells in aging.
作者信息
Agrawal Anshu, Agrawal Sudhanshu, Tay Jia, Gupta Sudhir
机构信息
Division of Basic and Clinical Immunology, University of California, Irvine, CA 92697, USA.
出版信息
J Clin Immunol. 2008 Jan;28(1):14-20. doi: 10.1007/s10875-007-9127-6. Epub 2007 Sep 9.
PMID:17828583
Abstract
Dendritic cells are central to the generation of both immunity and tolerance. This review focuses on the alterations in the functions of dendritic cells in aged and its consequences on both tolerance and immunity. We have discussed certain mechanisms responsible for the defective dendritic cell function associated with aging.
摘要
树突状细胞对于免疫和耐受的产生至关重要。本综述聚焦于衰老过程中树突状细胞功能的改变及其对耐受和免疫的影响。我们已经讨论了与衰老相关的树突状细胞功能缺陷的某些机制。
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