一名19岁女性的透明细胞宫颈腺癌。

Clear-cell endocervical adenocarcinoma in a 19-year-old woman.

作者信息

Stewart Jimmie, Bevans-Wilkins Kristen, Ye Changhong, Kurtycz Daniel F I

机构信息

Cytopathology Section, Department of Pathology and Laboratory Medicine, University of Wisconsin Medical School, 600 Highland Avenue, Madison, WI 53792, USA.

出版信息

Diagn Cytopathol. 2006 Dec;34(12):839-42. doi: 10.1002/dc.20569.

DOI:10.1002/dc.20569

PMID:17183758

Abstract

The incidence of adenocarcinoma of the cervix is increasing within the US, but this diagnostic category is not typically associated with teenaged patients. A report on a case of a 19-year-old woman, with no history of diethylbestrol exposure in uteri, diagnosed with clear-cell endocervical adenocarcinoma is made. Malignant glandular cells were detected on both conventional and Thin Prep gynecologic tests with histologic confirmation. Human papilloma virus (HPV) high-risk type results were negative in this particular case. The patient's unremarkable medical and sexual history prompted us to review the diagnostic criteria and pathogenesis of the disease.

摘要

在美国，宫颈腺癌的发病率正在上升，但这一诊断类别通常与青少年患者无关。本文报告了一例19岁女性病例，该患者在子宫内无己烯雌酚暴露史，被诊断为透明细胞宫颈内膜腺癌。在传统妇科检查和液基薄层制片检查中均检测到恶性腺细胞，并经组织学证实。在该特定病例中，人乳头瘤病毒（HPV）高危型检测结果为阴性。患者无明显的病史和性病史，促使我们对该疾病的诊断标准和发病机制进行了回顾。