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[嗜酸性肉芽肿的病因学研究]

[An etiological study of eosinophilic granuloma].

作者信息

Schmidt H, Krell D, Krell R

出版信息

Dtsch Zahn Mund Kieferheilkd Zentralbl. 1991;79(6):455-64.

PMID:1718455
Abstract

By means of the proof for the enzyme phenol oxidase (PO; EC 1.14.18.1) was investigated, whether the eosinophilic granuloma correspond to a cell mediated immunological defence reaction. The method allowed to determine the eosinophils rapidly and surely and give an overview on the frequency and distribution of these cells. By electron microscopy was Langerhans-cells identified in close contact to many eosinophils. Their granula shows manifold changes in their structure. The eosinophilic granuloma is a cell mediated defence reaction approximate to the type of a delayed hypersensitivity.

摘要

通过对酚氧化酶(PO;EC 1.14.18.1)的检测,研究嗜酸性肉芽肿是否对应一种细胞介导的免疫防御反应。该方法能够快速、准确地测定嗜酸性粒细胞,并对这些细胞的频率和分布进行概述。通过电子显微镜观察发现,朗格汉斯细胞与许多嗜酸性粒细胞紧密接触。它们的颗粒在结构上呈现出多种变化。嗜酸性肉芽肿是一种类似于迟发型超敏反应类型的细胞介导防御反应。

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