Rosenkilde P, Pedersen J F, Meyhoff H H
Department of Urology, Glostrup Hospital, University of Copenhagen, Denmark.
Br J Urol. 1991 Oct;68(4):387-9. doi: 10.1111/j.1464-410x.1991.tb15357.x.
The self-retaining intra-urethral device "Prostakath" was inserted in a consecutive series of 29 men with obstructive benign prostatic hypertrophy. Fifteen patients were relieved of prostatic symptoms for an observation period of 22 weeks (range 2-60). The spiral was removed in 14 cases (48%) at an average of 14 weeks (range 1-82) after insertion; in 9 patients this was because of urinary retention and in 5 it followed dislocation of the stent into the bladder. Five stents removed after 44 weeks of treatment (range 21-82) were severely calcified. Light microscopic investigation of the Spirals that were removed revealed no damage to the gold-plated surface. All patients with calcification had chronic urinary infection resistant to antibiotic treatment. We believe that infected urine is the major factor responsible for the calcification. We suggest that patients with recurrent urinary infection after insertion of the Prostakath should be closely followed up and checked for stone formation by a plain X-ray of the bladder region. It may be advisable to change the Prostakath in patients with resistant urinary tract infection at 6-monthly intervals.
在连续的29例梗阻性良性前列腺增生男性患者中插入了自固定尿道内装置“Prostakath”。15例患者在22周（范围2 - 60周）的观察期内前列腺症状得到缓解。14例（48%）在插入后平均14周（范围1 - 82周）取出螺旋装置；其中9例是因为尿潴留，5例是由于支架移位至膀胱。治疗44周（范围21 - 82周）后取出的5个支架严重钙化。对取出的螺旋装置进行光镜检查显示镀金表面未受损。所有钙化患者均患有对抗生素治疗耐药的慢性尿路感染。我们认为感染的尿液是导致钙化的主要因素。我们建议，插入“Prostakath”后反复发生尿路感染的患者应密切随访，并通过膀胱区域的X线平片检查是否形成结石。对于耐药性尿路感染患者，每隔6个月更换“Prostakath”可能是明智的。
