相似文献
1
Synthesis and SAR of 3,5-diamino-piperidine derivatives: novel antibacterial translation inhibitors as aminoglycoside mimetics.
Bioorg Med Chem Lett. 2007 Mar 1;17(5):1206-10. doi: 10.1016/j.bmcl.2006.12.024. Epub 2006 Dec 12.
2
Antibacterial activity in serum of the 3,5-diamino-piperidine translation inhibitors.
Bioorg Med Chem Lett. 2008 Jun 1;18(11):3369-75. doi: 10.1016/j.bmcl.2008.04.023. Epub 2008 Apr 13.
3
Structure-guided discovery of novel aminoglycoside mimetics as antibacterial translation inhibitors.
Antimicrob Agents Chemother. 2005 Dec;49(12):4942-9. doi: 10.1128/AAC.49.12.4942-4949.2005.
4
Structure-activity relationships of novel antibacterial translation inhibitors: 3,5-diamino-piperidinyl triazines.
Bioorg Med Chem Lett. 2006 Oct 15;16(20):5451-6. doi: 10.1016/j.bmcl.2006.07.052. Epub 2006 Aug 4.
5
Novel 2,5-dideoxystreptamine derivatives targeting the ribosomal decoding site RNA.
Bioorg Med Chem Lett. 2002 Dec 2;12(23):3367-72. doi: 10.1016/s0960-894x(02)00759-x.
6
Oligoribonuclease Contributes to Tolerance to Aminoglycoside and β-Lactam Antibiotics by Regulating KatA in Pseudomonas aeruginosa.
Antimicrob Agents Chemother. 2019 May 24;63(6). doi: 10.1128/AAC.00212-19. Print 2019 Jun.
7
Novel paromamine derivatives exploring shallow-groove recognition of ribosomal-decoding-site RNA.
Chembiochem. 2002 Dec 2;3(12):1223-8. doi: 10.1002/1439-7633(20021202)3:12<1223::AID-CBIC1223>3.0.CO;2-W.
8
Importance of the 6'-hydroxy group and its configuration for apramycin activity.
ChemMedChem. 2014 Sep;9(9):2074-83. doi: 10.1002/cmdc.201402146. Epub 2014 Jul 17.
9
Development of aminoglycoside antibiotics by carbohydrate chemistry.
Mini Rev Med Chem. 2012 Dec;12(14):1533-41. doi: 10.2174/138955712803832672.
10
Modification at the 2'-Position of the 4,5-Series of 2-Deoxystreptamine Aminoglycoside Antibiotics To Resist Aminoglycoside Modifying Enzymes and Increase Ribosomal Target Selectivity.
ACS Infect Dis. 2019 Oct 11;5(10):1718-1730. doi: 10.1021/acsinfecdis.9b00128. Epub 2019 Sep 13.
引用本文的文献
1
The evolution and application of RNA-focused small molecule libraries.
RSC Chem Biol. 2025 Feb 13;6(4):510-527. doi: 10.1039/d4cb00272e. eCollection 2025 Apr 2.
2
Tetrahydropyridines' Stereoselective Formation, How Lockdown Assisted in the Identification of the Features of Its Mechanism.
Molecules. 2022 Jul 7;27(14):4367. doi: 10.3390/molecules27144367.
3
Two novel piperidones induce apoptosis and antiproliferative effects on human prostate and lymphoma cancer cell lines.
Invest New Drugs. 2022 Oct;40(5):905-921. doi: 10.1007/s10637-022-01266-y. Epub 2022 Jul 6.
4
Robust, highly active, and stable supported Co(ii) nanoparticles on magnetic cellulose nanofiber-functionalized for the multi-component reactions of piperidines and alcohol oxidation.
RSC Adv. 2021 Jul 1;11(38):23192-23206. doi: 10.1039/d1ra00208b.
5
Frameworks for targeting RNA with small molecules.
J Biol Chem. 2021 Jan-Jun;296:100191. doi: 10.1074/jbc.REV120.015203. Epub 2020 Dec 20.
6
Highly functionalized piperidines: Free radical scavenging, anticancer activity, DNA interaction and correlation with biological activity.
J Adv Res. 2017 Oct 31;9:51-61. doi: 10.1016/j.jare.2017.10.010. eCollection 2018 Jan.
7
Ethyl 2,6-bis-(4-chloro-phen-yl)-4-(4-fluoro-anilino)-1-(4-fluoro-phen-yl)-1,2,5,6-tetra-hydro-pyridine-3-carboxyl-ate.
Acta Crystallogr Sect E Struct Rep Online. 2013 Mar 9;69(Pt 4):o506-7. doi: 10.1107/S1600536813006090. Print 2013 Apr 1.
8
Methyl 4-(4-fluoro-anilino)-1,2,6-tris-(4-fluoro-phen-yl)-1,2,5,6-tetra-hydro-pyri-dine-3-carboxyl-ate.
Acta Crystallogr Sect E Struct Rep Online. 2013 Mar 1;69(Pt 3):o373-4. doi: 10.1107/S160053681300370X. Epub 2013 Feb 9.
9
A fluorescence-based screen for ribosome binding antibiotics.
Anal Biochem. 2013 Mar 15;434(2):300-7. doi: 10.1016/j.ab.2012.12.003. Epub 2012 Dec 19.
10
Novel insights of structure-based modeling for RNA-targeted drug discovery.
J Chem Inf Model. 2012 Oct 22;52(10):2741-53. doi: 10.1021/ci300320t. Epub 2012 Sep 21.
本文引用的文献
1
Structure-activity relationships of novel antibacterial translation inhibitors: 3,5-diamino-piperidinyl triazines.
Bioorg Med Chem Lett. 2006 Oct 15;16(20):5451-6. doi: 10.1016/j.bmcl.2006.07.052. Epub 2006 Aug 4.
2
Antimicrobial resistance in gram-positive bacteria.
Am J Infect Control. 2006 Jun;34(5 Suppl 1):S11-9; discussion S64-73. doi: 10.1016/j.ajic.2006.05.220.
3
Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA site.
Chem Biol. 2006 Feb;13(2):129-38. doi: 10.1016/j.chembiol.2005.11.004.
4
Structure-guided discovery of novel aminoglycoside mimetics as antibacterial translation inhibitors.
Antimicrob Agents Chemother. 2005 Dec;49(12):4942-9. doi: 10.1128/AAC.49.12.4942-4949.2005.
5
Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding.
Nucleic Acids Res. 2005 Oct 7;33(17):5677-90. doi: 10.1093/nar/gki862. Print 2005.
6
Improving on nature: antibiotics that target the ribosome.
Curr Opin Microbiol. 2005 Oct;8(5):534-42. doi: 10.1016/j.mib.2005.08.004.
7
Defining the need for new antimicrobials: clinical and economic implications of resistance in the hospitalised patient.
Expert Opin Pharmacother. 2005 Jun;6(6):873-89. doi: 10.1517/14656566.6.6.873.
8
Molecular recognition by glycoside pseudo base pairs and triples in an apramycin-RNA complex.
Angew Chem Int Ed Engl. 2005 Apr 29;44(18):2694-2700. doi: 10.1002/anie.200500028.
9
2-Deoxystreptamine: central scaffold of aminoglycoside antibiotics.
Chem Rev. 2005 Mar;105(3):775-91. doi: 10.1021/cr0404085.
10
A structure-based strategy to identify new molecular scaffolds targeting the bacterial ribosomal A-site.
Bioorg Med Chem. 2004 Mar 1;12(5):935-47. doi: 10.1016/j.bmc.2003.12.023.
Zotero 插件