Hyllienmark Lars, Amark Per
Department of Neurology, Karolinska University Hospital, SE-17176 Stockholm, Sweden.
Eur J Paediatr Neurol. 2007 Mar;11(2):70-5. doi: 10.1016/j.ejpn.2006.11.005. Epub 2006 Dec 26.
Monitoring with continuous EEG (cEEG) has become a valuable tool in the adult neurointensive care unit. The benefits of cEEG or amplitude-integrated EEG in neonatal intensive care have also been described. The aim of the present study was to describe and evaluate the use of cEEG in a paediatric intensive care unit. The study is a description of children and adolescents with acute neurological disorders monitored by cEEG in a paediatric intensive care unit for more than 12h. The indication for cEEG and the outcome are reported for 54 patients during a 4-year period. Twelve patients were monitored for high intracranial pressure, eight of whom died. Fourteen were monitored due to suspected, but not detected, epilepsy, their underlying diagnoses being variable. Refractory status epilepticus was the reason for cEEG in 24 cases. All of these patients survived the acute phase of status epilepticus. Four patients had seizure activity on cEEG due to global anoxia; these were not classified as status epilepticus. In conclusion, in the paediatric intensive care unit the most important indication for cEEG monitoring is in patients with suspected refractory status epilepticus where it adds to the diagnosis and choice of treatment. Continuous EEG should therefore be part of the paediatric intensive care unit technical support to select and monitor, among children with critical neurological disorders, those with refractory status epilepticus.
在成人神经重症监护病房中,连续脑电图(cEEG)监测已成为一项重要工具。cEEG或振幅整合脑电图在新生儿重症监护中的益处也已得到描述。本研究的目的是描述和评估cEEG在儿科重症监护病房中的应用。该研究描述了在儿科重症监护病房接受cEEG监测超过12小时的患有急性神经系统疾病的儿童和青少年。报告了4年期间54例患者的cEEG指征及结果。12例患者因颅内压高接受监测,其中8例死亡。14例因疑似癫痫(但未确诊)接受监测,其潜在诊断各不相同。24例患者因难治性癫痫持续状态接受cEEG监测。所有这些患者均度过了癫痫持续状态的急性期。4例患者因全身性缺氧在cEEG上出现癫痫活动;这些未被归类为癫痫持续状态。总之,在儿科重症监护病房中,cEEG监测的最重要指征是疑似难治性癫痫持续状态的患者,它有助于诊断和治疗选择。因此,连续脑电图应成为儿科重症监护病房技术支持的一部分,以便在患有严重神经系统疾病的儿童中筛选和监测难治性癫痫持续状态患者。