相似文献
1
Mad2 overexpression promotes aneuploidy and tumorigenesis in mice.
Cancer Cell. 2007 Jan;11(1):9-23. doi: 10.1016/j.ccr.2006.10.019. Epub 2006 Dec 28.
2
The Mad1-Mad2 balancing act--a damaged spindle checkpoint in chromosome instability and cancer.
J Cell Sci. 2012 Sep 15;125(Pt 18):4197-206. doi: 10.1242/jcs.107037. Epub 2012 Oct 23.
3
Rb loss causes cancer by driving mitosis mad.
Cancer Cell. 2007 Jan;11(1):1-3. doi: 10.1016/j.ccr.2006.12.006.
4
Hec1 overexpression hyperactivates the mitotic checkpoint and induces tumor formation in vivo.
Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16719-24. doi: 10.1073/pnas.0803504105. Epub 2008 Oct 21.
5
MAD2DeltaC induces aneuploidy and promotes anchorage-independent growth in human prostate epithelial cells.
Oncogene. 2008 Jan 10;27(3):347-57. doi: 10.1038/sj.onc.1210633. Epub 2007 Jul 9.
6
Spindle assembly checkpoint, aneuploidy and tumorigenesis.
Cell Cycle. 2009 Nov 1;8(21):3440. doi: 10.4161/cc.8.21.9688. Epub 2009 Dec 1.
7
Mad2 Overexpression Uncovers a Critical Role for TRIP13 in Mitotic Exit.
Cell Rep. 2017 May 30;19(9):1832-1845. doi: 10.1016/j.celrep.2017.05.021.
8
Hormone-induced chromosomal instability in p53-null mammary epithelium.
Cancer Res. 2004 Aug 15;64(16):5608-16. doi: 10.1158/0008-5472.CAN-03-0629.
9
Up-regulation of the mitotic checkpoint component Mad1 causes chromosomal instability and resistance to microtubule poisons.
Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):E2205-14. doi: 10.1073/pnas.1201911109. Epub 2012 Jul 9.
10
Partial downregulation of MAD1 causes spindle checkpoint inactivation and aneuploidy, but does not confer resistance towards taxol.
Oncogene. 2005 Jun 16;24(26):4301-10. doi: 10.1038/sj.onc.1208589.
引用本文的文献
1
Linear ubiquitination of p31 by HOIP couples cytokine response with mitotic regulation.
Cell Biosci. 2025 Jun 3;15(1):75. doi: 10.1186/s13578-025-01416-8.
2
High Sugar Induced RCC2 Lactylation Drives Breast Cancer Tumorigenicity Through Upregulating MAD2L1.
Adv Sci (Weinh). 2025 Jun;12(21):e2415530. doi: 10.1002/advs.202415530. Epub 2025 Mar 27.
3
Role of spindle assembly checkpoint proteins in gametogenesis and embryogenesis.
Front Cell Dev Biol. 2025 Jan 22;12:1491394. doi: 10.3389/fcell.2024.1491394. eCollection 2024.
4
TRACERx analysis identifies a role for FAT1 in regulating chromosomal instability and whole-genome doubling via Hippo signalling.
Nat Cell Biol. 2025 Jan;27(1):154-168. doi: 10.1038/s41556-024-01558-w. Epub 2024 Dec 30.
5
TSG101 depletion dysregulates mitochondria and PML NBs, triggering MAD2-overexpressing interphase cell death (MOID) through AIFM1-PML-DAXX pathway.
Cell Death Dis. 2024 Nov 17;15(11):838. doi: 10.1038/s41419-024-07229-w.
6
Centromeres in cancer: Unraveling the link between chromosomal instability and tumorigenesis.
Med Oncol. 2024 Oct 1;41(11):254. doi: 10.1007/s12032-024-02524-0.
7
Chromosomal instability increases radiation sensitivity.
bioRxiv. 2024 Sep 19:2024.09.13.612942. doi: 10.1101/2024.09.13.612942.
8
Recent insights into the causes and consequences of chromosome mis-segregation.
Oncogene. 2024 Oct;43(43):3139-3150. doi: 10.1038/s41388-024-03163-5. Epub 2024 Sep 15.
9
Chromosome instability functions as a potential therapeutic reference by enhancing chemosensitivity to BCL-XL inhibitors in colorectal carcinoma.
Acta Pharmacol Sin. 2024 Nov;45(11):2420-2431. doi: 10.1038/s41401-024-01372-y. Epub 2024 Aug 26.
10
Polyploid giant cancer cells: origin, possible pathways of formation, characteristics, and mechanisms of regulation.
Front Cell Dev Biol. 2024 Jul 11;12:1410637. doi: 10.3389/fcell.2024.1410637. eCollection 2024.
本文引用的文献
1
Cell biology: nondisjunction, aneuploidy and tetraploidy.
Nature. 2006 Aug 17;442(7104):E9-10; discussion E10. doi: 10.1038/nature05139.
2
Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression.
J Cell Biol. 2006 Mar 13;172(6):847-60. doi: 10.1083/jcb.200506119.
3
The selective continued linkage of centromeres from mitosis to interphase in the absence of mammalian separase.
J Cell Biol. 2006 Mar 13;172(6):835-46. doi: 10.1083/jcb.200511126.
4
On the road to cancer: aneuploidy and the mitotic checkpoint.
Nat Rev Cancer. 2005 Oct;5(10):773-85. doi: 10.1038/nrc1714.
5
High-resolution genomic profiles of human lung cancer.
Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9625-30. doi: 10.1073/pnas.0504126102. Epub 2005 Jun 27.
6
Colonic tumorigenesis in BubR1+/-ApcMin/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability.
Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4365-70. doi: 10.1073/pnas.0407822102. Epub 2005 Mar 14.
7
APC/C-Cdc20-mediated degradation of cyclin B participates in CSF arrest in unfertilized Xenopus eggs.
Dev Biol. 2005 Mar 15;279(2):345-55. doi: 10.1016/j.ydbio.2004.12.025.
8
The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint.
Curr Biol. 2005 Feb 8;15(3):214-25. doi: 10.1016/j.cub.2005.01.038.
9
Oncogene addiction: sometimes a temporary slavery.
Cancer Cell. 2004 Dec;6(6):535-8. doi: 10.1016/j.ccr.2004.12.002.
10
Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control.
Nature. 2004 Aug 12;430(7001):797-802. doi: 10.1038/nature02820.
Zotero 插件