皮肤结节病治疗的最新进展。

Cutaneous sarcoidosis therapy updated.

作者信息

Badgwell Christy, Rosen Ted

机构信息

Dermatology Department, Baylor College of Medicine, and Houston Veterans Affairs Medical Center, Texas, USA.

出版信息

J Am Acad Dermatol. 2007 Jan;56(1):69-83. doi: 10.1016/j.jaad.2006.06.019.

DOI:10.1016/j.jaad.2006.06.019

PMID:17190623

Abstract

The widely accepted standard therapy for cutaneous sarcoidosis includes corticosteroids, antimalarials, and methotrexate. However, a better understanding of the basic immunopathogenic properties of sarcoidosis has elucidated a number of steps critical to the persistence and progression of disease that may be vulnerable to treatment by targeted therapy. This article reviews both standard and newer therapeutic options for cutaneous sarcoidosis.

摘要

皮肤结节病广泛接受的标准疗法包括使用皮质类固醇、抗疟药和甲氨蝶呤。然而，对结节病基本免疫发病机制特性的深入了解，阐明了一些对疾病持续和进展至关重要的步骤，而这些步骤可能易于通过靶向治疗进行干预。本文综述了皮肤结节病的标准治疗方案和新的治疗选择。