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“狼疮”的皮肤表现:系统性红斑狼疮及其他。

Cutaneous Manifestations of "Lupus": Systemic Lupus Erythematosus and Beyond.

作者信息

Cooper Elizabeth E, Pisano Catherine E, Shapiro Samantha C

机构信息

Department of Dermatology, Dell Medical School at the University of Texas, Austin 78701, USA.

Department of Medicine, Division of Rheumatology, Dell Medical School at the University of Texas, Austin 78701, USA.

出版信息

Int J Rheumatol. 2021 May 18;2021:6610509. doi: 10.1155/2021/6610509. eCollection 2021.

Abstract

Lupus, Latin for "wolf," is a term used to describe many dermatologic conditions, some of which are related to underlying systemic lupus erythematosus, while others are distinct disease processes. Cutaneous lupus erythematosus includes a wide array of visible skin manifestations and can progress to systemic lupus erythematosus in some cases. Cutaneous lupus can be subdivided into three main categories: acute cutaneous lupus erythematosus, subacute cutaneous lupus erythematosus, and chronic cutaneous lupus erythematosus. Physical exam, laboratory studies, and histopathology enable differentiation of cutaneous lupus subtypes. This differentiation is paramount as the subtype of cutaneous lupus informs upon treatment, disease monitoring, and prognostication. This review outlines the different cutaneous manifestations of lupus erythematosus and provides an update on both topical and systemic treatment options for these patients. Other conditions that utilize the term "lupus" but are not cutaneous lupus erythematosus are also discussed.

摘要

“狼疮”一词源于拉丁语“lupus”,用于描述多种皮肤病状况,其中一些与潜在的系统性红斑狼疮相关,而另一些则是独立的疾病进程。皮肤型红斑狼疮包括一系列可见的皮肤表现,在某些情况下可进展为系统性红斑狼疮。皮肤型狼疮可细分为三大类:急性皮肤型红斑狼疮、亚急性皮肤型红斑狼疮和慢性皮肤型红斑狼疮。体格检查、实验室检查和组织病理学有助于区分皮肤型狼疮的亚型。这种区分至关重要,因为皮肤型狼疮的亚型为治疗、疾病监测和预后提供依据。本综述概述了红斑狼疮的不同皮肤表现,并提供了这些患者局部和全身治疗选择的最新情况。还讨论了其他使用“狼疮”一词但并非皮肤型红斑狼疮的病症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0b3/8154312/ba5232aa0fbb/IJR2021-6610509.001.jpg

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