Plankensteiner Kristof, Reiner Hannes, Rode Bernd M
Division of Theoretical Chemistry, Institute of General, Inorganic, and Theoretical Chemistry, University of Innsbruck, Innrain 52a, A-6020 Innsbruck.
Chem Biodivers. 2004 Sep;1(9):1308-15. doi: 10.1002/cbdv.200490093.
To re-enact the long way to the origin of life with today's chemical methods, many steps have to be investigated in the light of a primordial scenario deduced from geochemical research. After the formation of our planet and its atmosphere, prebiotic chemical evolution started its course with the formation of the first building blocks for the formation of biomolecules. In the case of proteins, those building blocks were amino acids that had to be formed in the primitive atmosphere, and then had to react to peptides and proteins as the main pillar of first life. In this paper, we describe the processes in the primordial atmosphere according to contemporary geochemical knowledge leading to the synthesis of amino acids until the formation of homochiral peptides, and, thus, show a plausible pathway towards the origin of life.
要用当今的化学方法重现生命起源的漫长历程,必须根据地球化学研究推断出的原始情景,对许多步骤进行研究。在我们的星球及其大气层形成之后,前生物化学进化随着生物分子形成的第一批构件的形成而开始。就蛋白质而言,这些构件是氨基酸,它们必须在原始大气中形成,然后必须反应生成肽和蛋白质,作为最初生命的主要支柱。在本文中,我们根据当代地球化学知识描述了原始大气中导致氨基酸合成直至同手性肽形成的过程,从而展示了一条通往生命起源的合理途径。