小花山麻杆叶的化学成分及抗氧化活性
Chemical constituents and antioxidant activity of Mallotus roxburghianus leaves.
作者信息
Rana Virendra S, Rawat Mohan S M, Pant Geeta, Nagatsu Akito
机构信息
Department of Chemistry, HNB Garhwal University, Srinagar (Garhwal)-246174, Uttaranchal, India.
出版信息
Chem Biodivers. 2005 Jun;2(6):792-8. doi: 10.1002/cbdv.200590057.
Mallotus roxburghianus is used in the traditional medicine in North-Eastern India, but previously no work has been done on the identification of bioactive compounds. Two new compounds, 3-(1-C-beta-D-glucopyranosyl)-2,6-dihydroxy-5-methoxybenzoic acid (6) and 2,4,8,9,10-pentahydroxy-3,7-dimethoxyanthracene-6-O-beta-D-rhamnopyranoside (7) together with beta-sitosterol (1), stigmasterol (2), betulinic acid (3), 4-hydroxybenzoic acid (4), beta-sitosterol-beta-D-glucoside (5), and bergenin (8) were isolated and identified from the leaves of M. roxburghianus. The chloroform soluble portion of the alcoholic extract of leaf, and compounds 3, 6, 7, and 8 exhibited encouraging antioxidant activities.
印度东北部传统医学中使用了罗氏野桐，但此前尚未开展生物活性化合物的鉴定工作。从罗氏野桐叶中分离并鉴定出两种新化合物，3-(1-C-β-D-吡喃葡萄糖基)-2,6-二羟基-5-甲氧基苯甲酸(6)和2,4,8,9,10-五羟基-3,7-二甲氧基蒽-6-O-β-D-鼠李糖苷(7)，以及β-谷甾醇(1)、豆甾醇(2)、桦木酸(3)、4-羟基苯甲酸(4)、β-谷甾醇-β-D-葡萄糖苷(5)和岩白菜素(8)。叶醇提取物的氯仿可溶部分以及化合物3、6、7和8表现出令人鼓舞的抗氧化活性。
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