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[2002年至2004年期间抗抑郁药的消费演变]

[Evolution in consumption of anti-depressants during the years 2002 to 2004].

作者信息

Serna Arnáiz Catalina, Galván Santiago Leonardo, Gascó Eguíluz Eduardo, Santafé Soler Plácido, Martín Gracia Elisabeth, Vila Parrot Teresa

机构信息

Servicio de Atención Primaria. Universidad de Lleida. España.

出版信息

Aten Primaria. 2006 Nov 15;38(8):456-60. doi: 10.1157/13094803.

Abstract

OBJECTIVE

To analyse the use of antidepressants from 2002 to 2004 and the length of treatment.

DESIGN

Cross-sectional, descriptive study of antidepressant drugs prescribed through the National Health System during 2002-2004.

SETTING

Lleida Health Region, Spain.

PARTICIPANTS

A total of 54,890 patients received an antidepressant drug between 2002 and 2004.

MEASUREMENTS

Age, sex, medicine, prescription period, centre.

RESULTS

The prevalence of antidepressant treatment was: 8.4% in 2002 (368,976 inhabitants); 8.6% in 2003 (376,638 inhabitants); and 8.7% in 2004 (388,148 inhabitants). The increase in antidepressant treatment in 2004 over 2002 was 9.4%. Prevalence among men was 5.4% and women, 12.7%. The distribution according to antidepressant classes was: selective serotonin reuptake inhibitors, 73.7%; tricyclic antidepressants, 26.2%; heterocyclic antidepressants, 10%, and monoamine oxidase inhibitors, 0.1%. The duration of treatment was 1 to 3 months (43%), 4 to 12 months (22.7%), 13 to 24 months (14.4%), and over 24 months (19.9%).

CONCLUSIONS

A steady increase in the use of antidepressants is being observed, predominantly new drugs. Regarding the length of treatment, a high proportion of patients are treated for under 4 months, which does not follow recent recommendations in the scientific literature for treatment of depression. This is a major element of inefficiency in the health system.

摘要

目的

分析2002年至2004年抗抑郁药的使用情况及治疗时长。

设计

对2002 - 2004年通过国家卫生系统开具的抗抑郁药物进行横断面描述性研究。

地点

西班牙莱里达卫生区。

参与者

2002年至2004年期间共有54,890名患者接受了抗抑郁药物治疗。

测量指标

年龄、性别、药物、处方时长、治疗中心。

结果

抗抑郁治疗的患病率分别为:2002年8.4%(368,976名居民);2003年8.6%(376,638名居民);2004年8.7%(388,148名居民)。2004年相较于2002年抗抑郁治疗的增幅为9.4%。男性患病率为5.4%,女性为12.7%。按抗抑郁药类别分布为:选择性5-羟色胺再摄取抑制剂,73.7%;三环类抗抑郁药,26.2%;杂环类抗抑郁药,10%;单胺氧化酶抑制剂,0.1%。治疗时长为1至3个月(43%)、4至12个月(22.7%)、13至24个月(14.4%)以及超过24个月(19.9%)。

结论

观察到抗抑郁药的使用呈稳步增长,主要是新药。关于治疗时长,很大一部分患者治疗时间不足4个月,这不符合科学文献中近期关于抑郁症治疗的建议。这是卫生系统效率低下的一个主要因素。

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