Bukowiecka-Matusiak Małgorzata, Woźniak Lucyna A
Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, 90-363 łódź, Poland.
Postepy Biochem. 2006;52(3):229-38.
Deoxyribonucleic acid (DNA) is a biopolymer of nucleotides, usually adopting a double-stranded helical form in cells, with complementary base pairing holding the two strands together. The most stable is B-DNA conformation, although numerous other double helical structures can occur under specific conditions (A-DNA, Z-DNA, P-DNA). The existence of multiple-stranded (triplex, tetraplex) forms in vivo and their biological function in cells are subject of intensive studies.
脱氧核糖核酸(DNA)是一种核苷酸生物聚合物,在细胞中通常呈双链螺旋形式,互补碱基配对将两条链维系在一起。最稳定的是B-DNA构象,不过在特定条件下也会出现许多其他双螺旋结构(A-DNA、Z-DNA、P-DNA)。体内多链(三链、四链)形式的存在及其在细胞中的生物学功能是深入研究的课题。