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[包皮环切术后患者的阴茎鳞状细胞癌:17例报告]

[Penile squamous carcinoma in circumcised patients: a report 17 cases].

作者信息

Wan Qun, Li Zhong-yi, Shen Zhou-jun, Zhu Xuan-wen, Zhang Zhi-gen, Cai Song-liang

机构信息

Department of Urology, First Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China.

出版信息

Zhonghua Nan Ke Xue. 2006 Dec;12(12):1108-9.

Abstract

OBJECTIVE

To discuss the diagnosis and treatment of penile carcinoma in circumcised men.

METHODS

We reviewed 17 cases of penile carcinoma detected 1 month to 16 years after circumcision performed in our hospital from January, 1997 to December, 2004.

RESULTS

Of the total number, 11 cases were diagnosed as penile carcinoma 1 - 12 months and the others 3 - 16 years after the circumcision. Sixteen of them were treated by partial penectomy, anti 1 first by extensive circumcision and later by partial and total penectomy successively after recurrence. Cloquet nodes biopsy showed 16 cases to be pathologically well-differentiated and I case moderately differentiated penile squamous carcinoma. One died of extensive metastasis, but the other 16 remained disease-free survivals.

CONCLUSION

Circumcised adult men, especially those over 40 years of age, are likely to develop penile carcinoma. Patients with inflammation, plaque or ulcer in the prepuce should be checked by pathological biopsy and followed up closely. For Stage-I penile squamous carcinoma, partial penectomy is shown to be an effective therapeutic option, and Cloquet's nodes biopsy is necessary for all patients.

摘要

目的

探讨包皮环切术后男性阴茎癌的诊断与治疗。

方法

回顾性分析我院1997年1月至2004年12月期间行包皮环切术后1个月至16年发现的17例阴茎癌病例。

结果

17例中,11例在包皮环切术后1 - 12个月被诊断为阴茎癌,其余6例在术后3 - 16年被诊断。其中16例行阴茎部分切除术,1例最初行包皮环切术,复发后先后行阴茎部分切除术和阴茎全切术。腹股沟深淋巴结活检显示,16例为高分化阴茎鳞状细胞癌,1例为中分化。1例因广泛转移死亡,其余16例无瘤生存。

结论

包皮环切术后成年男性,尤其是40岁以上者,仍有可能发生阴茎癌。对包皮有炎症、斑块或溃疡者应行病理活检并密切随访。对于Ⅰ期阴茎鳞状细胞癌,阴茎部分切除术是有效的治疗选择,所有患者均需行腹股沟深淋巴结活检。

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