Trinka Eugen, Kienpointner Gudrun, Unterberger Iris, Luef Gerhard, Bauer Gerhard, Doering Lisa Bartha, Doering Stephan
Department of Neurology, Innsbruck Medical University, Innsbruck, Austria.
Epilepsia. 2006 Dec;47(12):2086-91. doi: 10.1111/j.1528-1167.2006.00828.x.
To assess the prevalence of psychiatric disturbances among patients with juvenile myoclonic epilepsy (JME).
Forty-three patients with JME (22 female, 21 male, mean age 32.4+/-13, range 15-63) were assessed by means of the Structured Clinical Interviews for DSM-IV (SCID-I and SCID-II). Current and lifetime psychiatric diagnoses were assigned.
Thirty-five percent of the JME patients suffered from one or more psychiatric disorders (Axis I and Axis II). Personality disorders were present in 23% and Axis I disorders in 19%. Altogether, 47% had a psychiatric disorder at any time of their life.
Psychiatric diagnoses are slightly higher than in representative community samples. The substantially increased number of personality disorders in JME patients might be attributed to frontal lobe deficits.
评估青少年肌阵挛癫痫（JME）患者中精神障碍的患病率。
采用针对《精神疾病诊断与统计手册》第四版（DSM-IV）的结构化临床访谈（SCID-I和SCID-II）对43例JME患者（22例女性，21例男性，平均年龄32.4±13岁，范围15 - 63岁）进行评估。确定当前和终生的精神疾病诊断。
35%的JME患者患有一种或多种精神障碍（轴I和轴II）。人格障碍的患病率为23%，轴I障碍为19%。总体而言，47%的患者在其一生中的任何时候都患有精神障碍。
精神疾病诊断略高于代表性社区样本。JME患者中人格障碍数量的大幅增加可能归因于额叶功能缺陷。
