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多相微流体技术:从流动特性到化学与材料合成

Multiphase microfluidics: from flow characteristics to chemical and materials synthesis.

作者信息

Günther Axel, Jensen Klavs F

机构信息

Department of Chemical Engineering, MIT, 66-501, Cambridge, MA 02139, USA.

出版信息

Lab Chip. 2006 Dec;6(12):1487-503. doi: 10.1039/b609851g. Epub 2006 Sep 27.

DOI:10.1039/b609851g
PMID:17203152
Abstract

We review transport characteristics of pressure-driven, multiphase flows through microchannel networks tens of nanometres to several hundred of micrometres wide with emphasis on conditions resulting in enhanced mixing and reduced axial dispersion. Dimensionless scaling parameters useful in characterizing multiphase flows are summarized along with experimental flow visualization techniques. Static and dynamic stability considerations are also included along with methods for stabilizing multiphase flows through surface modifications. Observed gas-liquid and immiscible liquid-liquid flows are summarized in terms of flow regime diagrams and the different flows are related to applications in chemistry and materials synthesis. Means to completely separate multiphase flows on the microscale and guidelines for design of scalable multiphase systems are also discussed.

摘要

我们回顾了压力驱动的多相流在宽度从几十纳米到几百微米的微通道网络中的传输特性,重点关注导致增强混合和降低轴向扩散的条件。总结了用于表征多相流的无量纲缩放参数以及实验流动可视化技术。还包括静态和动态稳定性考量以及通过表面改性来稳定多相流的方法。根据流型图总结了观察到的气-液和不混溶液-液流动情况,并将不同的流动与化学和材料合成中的应用相关联。还讨论了在微尺度上完全分离多相流的方法以及可扩展多相系统的设计指南。

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