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[借助卵子捐赠实现高龄妊娠]

[Pregnancy at a later age with the help of oocyte donation].

作者信息

Kortman M, de Wert G M W R, Fauser B C J M, Macklon N S

机构信息

Universitair Medisch Centrum Utrecht, afd. Voortplantingsgeneeskunde en Gynaecologie, Postbus 85.500, 3508 GA Utrecht.

出版信息

Ned Tijdschr Geneeskd. 2006 Nov 25;150(47):2591-5.

Abstract

An increasing number of women are delaying childbirth until an age when their fertility has significantly declined. Oocyte donation provides the opportunity for women to successfully conceive regardless of age. In The Netherlands, in 1997 the age limit for oocyte donation treatment was set at 45 years. The most important objections to pregnancy in older women are the medical risks for mother and child, the application of fertility treatments beyond the natural reproductive age and the psychosocial consequences for the child. However, based on international experience and recent data concerning the risks of pregnancy after oocyte donation in older women, it is proposed to increase the maximum age limit for this procedure to 50 years.

摘要

越来越多的女性推迟生育,直到她们的生育能力显著下降的年龄。卵子捐赠为女性提供了无论年龄多大都能成功受孕的机会。在荷兰,1997年卵子捐赠治疗的年龄限制设定为45岁。对老年女性怀孕最重要的反对意见是母婴的医疗风险、超出自然生殖年龄的生育治疗的应用以及对孩子的心理社会影响。然而,基于国际经验和近期有关老年女性卵子捐赠后怀孕风险的数据,建议将该程序的最大年龄限制提高到50岁。

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