Carmona-Saez Pedro, Chagoyen Monica, Tirado Francisco, Carazo Jose M, Pascual-Montano Alberto
BioComputing Unit, National Center of Biotechnology (CNB-CSIC), C/Darwin 3, Campus Universidad Autónoma de Madrid, 28049 Madrid, Spain.
Genome Biol. 2007;8(1):R3. doi: 10.1186/gb-2007-8-1-r3.
We present GENECODIS, a web-based tool that integrates different sources of information to search for annotations that frequently co-occur in a set of genes and rank them by statistical significance. The analysis of concurrent annotations provides significant information for the biologic interpretation of high-throughput experiments and may outperform the results of standard methods for the functional analysis of gene lists. GENECODIS is publicly available at http://genecodis.dacya.ucm.es/.
我们介绍了GENECODIS,这是一个基于网络的工具,它整合了不同的信息来源,以搜索在一组基因中频繁共现的注释,并根据统计显著性对它们进行排名。对并发注释的分析为高通量实验的生物学解释提供了重要信息,并且可能优于基因列表功能分析的标准方法的结果。GENECODIS可在http://genecodis.dacya.ucm.es/上公开获取。