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[病态肥胖的外科治疗]

[Surgical treatment of morbid obesity].

作者信息

Aasheim Erlend T, Mala Tom, Søvik Torgeir T, Kristinsson Jon, Bøhmer Thomas

机构信息

Medisinsk klinikk, Aker universitetssykehus, 0514 Oslo.

出版信息

Tidsskr Nor Laegeforen. 2007 Jan 4;127(1):38-42.

Abstract

BACKGROUND

Patients with morbid obesity are prone to weight-related disease, reduced quality of life and shortened life expectancy. Long-term weight loss is unsatisfactory with conservative treatment and weight-reducing surgery is increasingly performed in all Norwegian health regions.

METHODS

This review is based on electronic database searches. We describe the two procedures most commonly performed in Norway, i.e. gastric bypass and biliopancreatic diversion with duodenal switch, including preoperative workup and expected results after surgery. The domestic use of different surgical techniques is also outlined.

RESULTS

In Norway, around 750 bariatric procedures were planned in 2006. Gastric bypass yields a weight reduction of 30% two years after the operative. Resolution of type 2-diabetes, hypertension, hyperlipidemia, and obstructive sleep apnea has been demonstrated in most patients. A majority of patients report improved quality of life. Procedure-related mortality is less than 1% and surgical complications occur in approximately 20%. Nutritional deficiencies are frequent. Weight loss is somewhat greater after biliopancreatic diversion with duodenal switch, but the procedure is more complex. Life-long follow-up is recommended after bariatric surgery.

INTERPRETATION

In selected patients with morbid obesity, bariatric surgery is a viable treatment. However, prospective long- term studies are needed.

摘要

背景

病态肥胖患者易患与体重相关的疾病,生活质量下降,预期寿命缩短。保守治疗的长期减肥效果不理想,挪威所有健康地区越来越多地开展减肥手术。

方法

本综述基于电子数据库检索。我们描述了挪威最常实施的两种手术,即胃旁路手术和胆胰转流并十二指肠转位术,包括术前检查和术后预期结果。还概述了国内不同手术技术的使用情况。

结果

2006年挪威计划实施约750例减肥手术。胃旁路手术术后两年体重减轻30%。大多数患者的2型糖尿病、高血压、高脂血症和阻塞性睡眠呼吸暂停得到缓解。大多数患者报告生活质量有所改善。手术相关死亡率低于1%,手术并发症发生率约为20%。营养缺乏很常见。胆胰转流并十二指肠转位术后体重减轻幅度更大,但该手术更复杂。减肥手术后建议进行终身随访。

解读

对于选定的病态肥胖患者,减肥手术是一种可行的治疗方法。然而,需要进行前瞻性长期研究。

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