Kemper Markus J, Mueller-Wiefel Dirk E
Pediatric Nephrology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.
Eur J Pediatr. 2007 May;166(5):393-8. doi: 10.1007/s00431-006-0368-9. Epub 2007 Jan 5.
Although clinical outcome data on fetuses with oligohydramnios of renal origin are scarce, prognosis is regarded as poor due to a high risk of renal dysfunction and pulmonary hypoplasia. This review aims to summarize the current knowledge and clinical experience with patients presenting antenatally with renal oligohydramnios. By reviewing the underlying mechanisms, complications, and outcome data, we hope to further improve antenatal counseling and postnatal care. We conclude that prognosis of ROH has changed in recent years. While early data before the introduction of sophisticated neonatal intensive care and renal replacement therapy indicated a poor prognosis, nowadays, a much more optimistic prognosis of children after renal oligohydramnios can be expected from the recent publications in the literature.
虽然关于肾源性羊水过少胎儿的临床结局数据稀缺，但由于存在肾功能障碍和肺发育不全的高风险，其预后被认为较差。本综述旨在总结目前关于产前出现肾源性羊水过少患者的知识和临床经验。通过回顾潜在机制、并发症和结局数据，我们希望进一步改善产前咨询和产后护理。我们得出结论，近年来肾源性羊水过少的预后已有所改变。虽然在引入先进的新生儿重症监护和肾脏替代疗法之前的早期数据表明预后较差，但如今，从文献中的最新出版物可以预期，肾源性羊水过少患儿的预后要乐观得多。
