急性HIV感染的筛查：经验教训

Screening for acute HIV infection: lessons learned.

作者信息

Stekler Joanne, Maenza Janine, Stevens Claire E, Swenson Paul D, Coombs Robert W, Wood Robert W, Campbell Mary S, Nickle David C, Collier Ann C, Golden Matthew R

机构信息

Department of Medicine, University of Washington, Seattle, WA, USA.

出版信息

Clin Infect Dis. 2007 Feb 1;44(3):459-61. doi: 10.1086/510747. Epub 2006 Dec 20.

DOI:10.1086/510747

PMID:17205460

Abstract

Human immunodeficiency virus (HIV) nucleic acid testing is increasingly being used by researchers and public health screening programs to identify highly infectious, HIV antibody-negative individuals with acute HIV infection. We present cases to illustrate unusual instances of acute HIV screening, which include "window period" testing and the discovery of low-level HIV RNA.

摘要

研究人员和公共卫生筛查项目越来越多地使用人类免疫缺陷病毒（HIV）核酸检测来识别具有高传染性、HIV抗体阴性的急性HIV感染个体。我们通过病例来说明急性HIV筛查中的一些特殊情况，包括“窗口期”检测以及低水平HIV RNA的发现。