HIV/AIDS Division, University of California, San Francisco, San Francisco, CA 94110, USA.
J Infect Dis. 2010 Apr 15;201 Suppl 1:S7-15. doi: 10.1086/650393.
Rapid diagnostic tests that might be capable of detecting human immunodeficiency virus (HIV) antigens or nucleic acids represent the possibility of merging 2 key advancements in HIV testing: rapid testing and detection of acute HIV infection. In this article, we review the public health goals of rapid HIV testing and acute HIV testing and explore how rapid tests to directly detect HIV antigens or nucleic acids might alter current approaches to HIV case identification in clinical and public health screening settings. We discuss the specific types of HIV screening programs and settings in which direct viral rapid testing would offer an important advantage. Finally, we suggest priorities in operations research that must be achieved to pave the way for the future introduction of direct rapid viral testing technologies in the HIV testing marketplace.
快速诊断检测方法可能能够检测到人类免疫缺陷病毒 (HIV) 抗原或核酸，这代表着 HIV 检测的 2 项关键进展：快速检测和急性 HIV 感染检测的融合。在本文中，我们回顾了快速 HIV 检测和急性 HIV 检测的公共卫生目标，并探讨了直接检测 HIV 抗原或核酸的快速检测方法如何改变当前在临床和公共卫生筛查环境中识别 HIV 病例的方法。我们讨论了直接病毒快速检测将提供重要优势的特定类型的 HIV 筛查计划和环境。最后，我们建议在运营研究中必须实现的优先事项，为未来在 HIV 检测市场中引入直接快速病毒检测技术铺平道路。
