Kucharczyk Piotr, Michałkiewicz Dariusz, Kucharczyk Aleksandra
Wojskowy Instytut Medyczny w Warszawie, Szpitalny Oddzial Ratunkowy CSK MON.
Pol Merkur Lekarski. 2006 Oct;21(124):367-71.
The use of several groups of medications may result in thyroid dysfunction. So far the best known medication is amiodarone. The role of other medications and diagnostic agents in causing thyroid dysfunction is quite often forgotten. We presented medications and diagnostic agents commonly used in medical day-to-day practice. We described other than amiodarone iodinated agents and quoted recently published European guidelines in using iodinate contrast agents. We focused on lithium and psychiatric drugs and mechanism of their toxic impact on thyroid gland. These agents are important as they are applied for years (including children). At the end the impact of cytokines on thyroid gland was discussed, medications ever more widely applied in anti-viral and anti-neoplastic therapy.
使用几组药物可能会导致甲状腺功能障碍。迄今为止,最广为人知的药物是胺碘酮。其他药物和诊断剂在引起甲状腺功能障碍方面的作用常常被遗忘。我们介绍了医学日常实践中常用的药物和诊断剂。我们描述了除胺碘酮之外的含碘剂,并引用了最近发布的关于使用碘造影剂的欧洲指南。我们重点关注了锂和精神药物及其对甲状腺的毒性作用机制。这些药物很重要,因为它们已经使用多年(包括儿童)。最后讨论了细胞因子对甲状腺的影响,这些细胞因子在抗病毒和抗肿瘤治疗中应用越来越广泛。