Romagosa Cleofé, Ordi Jaume, Saute Francisco, Quintó Llorenç, Machungo Fernanda, Ismail Mamudo R, Carrilho Carla, Osman Nafissa, Alonso Pedro L, Menendez Clara
Department of Pathology, Hospital Clínic, University of Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
Trop Med Int Health. 2007 Jan;12(1):62-7. doi: 10.1111/j.1365-3156.2006.01755.x.
To evaluate the impact of malaria on maternal death through the analysis of the seasonal variations of crude and malaria-specific maternal mortality rates.
All maternal deaths and live births occurring at Maputo Central Hospital, located in an urban area, between January 2001 and December 2003, were retrospectively recorded. Clinical diagnoses of the causes of death and period of the year were analysed.
Two hundred and seventy-eight deaths were recorded. The overall crude maternal mortality rate was 995/100 000 live births. Malaria was the most frequent cause of maternal death, accounting for 23%. Crude and malaria-specific maternal mortality rates showed a similar pattern of seasonal variation, with peaks at the beginning and the end of the malaria transmission season. The malaria-specific maternal mortality rate was significantly higher during the rainy seasons (rate ratio 1.919; 95% CI 1.061, 3.470; P = 0.031).
Malaria may contribute to maternal mortality in highly endemic countries in sub-Saharan Africa, at least in urban areas. Efforts to improve malaria control in pregnancy may have an impact on maternal mortality in sub-Saharan Africa.
通过分析孕产妇粗死亡率和疟疾特异性死亡率的季节性变化，评估疟疾对孕产妇死亡的影响。
回顾性记录2001年1月至2003年12月期间发生在市区马普托中心医院的所有孕产妇死亡和活产情况。分析死亡原因的临床诊断和年份。
记录了278例死亡。孕产妇总体粗死亡率为995/10万活产。疟疾是孕产妇死亡最常见的原因，占23%。孕产妇粗死亡率和疟疾特异性死亡率呈现相似的季节性变化模式，在疟疾传播季节开始和结束时出现峰值。雨季期间疟疾特异性孕产妇死亡率显著更高（率比1.919；95%置信区间1.061, 3.470；P = 0.031）。
在撒哈拉以南非洲的高流行国家，疟疾可能导致孕产妇死亡，至少在城市地区如此。加强孕期疟疾控制的努力可能会对撒哈拉以南非洲的孕产妇死亡率产生影响。
