Hu J-J, Baek S, Humphrey J D
Department of Biomedical Engineering, Texas A&M University, College Station, TX 77843-3120, USA.
J Biomech. 2007;40(11):2559-63. doi: 10.1016/j.jbiomech.2006.11.007. Epub 2007 Jan 4.
Vascular cells are very responsive to even subtle changes in their local mechanical environment, thus there is a pressing need to quantify normal states of stress and strain as well as any perturbations from these normal states. Toward this end, we must quantify constitutive behaviors for both normal and adapted (maladapted) arteries. In this note, we report the first quantification of changes in the biaxial mechanical behavior of the passive basilar artery due to hypertension.
血管细胞对其局部力学环境中即使是细微的变化也非常敏感,因此迫切需要量化应力和应变的正常状态以及与这些正常状态的任何偏差。为此,我们必须量化正常和适应性(适应不良)动脉的本构行为。在本报告中,我们首次量化了高血压导致的被动基底动脉双轴力学行为的变化。