大叶刺蒴麻中的生物碱。

Alkaloids from Sarcomelicope megistophylla.

作者信息

Mitaku Sofia, Fokialakis Nikolas, Magiatis Prokopios, Tillequin François

机构信息

Department of Pharmacognosy and Chemistry of Natural Products, Faculty of Pharmacy, University of Athens, Athens 15771, Greece.

出版信息

Fitoterapia. 2007 Feb;78(2):169-70. doi: 10.1016/j.fitote.2006.10.003. Epub 2006 Nov 14.

DOI:10.1016/j.fitote.2006.10.003

PMID:17207940

Abstract

Two new alkaloids were isolated from the bark of Sarcomelicope megistophylla. Cyclomegistine B (1), a new quinolone alkaloid, that possesses a rare cyclobuta[b]quinoline ring system and sarcomejine B (2) which is a quinolone alkaloid with an unusual side chain. The structure of both compounds was elucidated on the basis of MS data and extensive NMR studies.

摘要

从大叶肉托果的树皮中分离出两种新生物碱。环肉托果碱B（1），一种新的喹诺酮生物碱，具有罕见的环丁烷[b]喹啉环系，以及肉托果碱B（2），它是一种带有不寻常侧链的喹诺酮生物碱。基于质谱数据和广泛的核磁共振研究阐明了这两种化合物的结构。