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863例患者行努氏修复术后的感染并发症

Infectious complications after the Nuss repair in a series of 863 patients.

作者信息

Shin Susanna, Goretsky Michael J, Kelly Robert E, Gustin Tina, Nuss Donald

机构信息

Department of Surgery, Eastern Virginia Medical School, Norfolk, VA 23507, USA.

出版信息

J Pediatr Surg. 2007 Jan;42(1):87-92. doi: 10.1016/j.jpedsurg.2006.09.057.

Abstract

PURPOSE

A nemesis of surgical implants is infection. We evaluated the various infectious complications after Nuss repair of pectus excavatum in 863 patients over 18 years.

METHODS

After institutional review board approval, a retrospective review of a prospectively gathered database of patients was performed who underwent minimally invasive repair of pectus excavatum and developed an infection. All patients received intravenous antibiotics before surgery continuing until discharge. Patients with a persistent fever after operation were discharged with oral antibiotics.

RESULTS

From January 1987 to September 2005, 863 patients underwent a minimally invasive pectus excavatum repair and 13 (1.5%) developed postoperative infections. These included 6 bar infections, 4 cases of cellulitis, and 3 stitch abscesses. Cellulitis was defined as erythema and warmth which responded to a single course of antibiotics. Bar infections were defined as an abscess in contact with the bar. Surgical drainage and long-term antibiotics resolved 3 of these abscesses, whereas 3 patients required early bar removal (1 after 3 months and 2 after 18 months). Cultures identified a single organism in each case and Staphylococcus aureus was the most common organism (83%) identified, and all being methicillin sensitive. All infections occurred on the side of the stabilizer if a stabilizer had been placed.

CONCLUSIONS

Infectious complications after Nuss repair are uncommon and occurred in 1.5% of our patients. Published rates of postoperative infection range from 1.0% to 6.8%. Superficial infections responded to antibiotics alone. Bar infection occurred in only 0.7% and required surgical drainage and long-term antibiotics. Only 3 of these (50% of bar infections and 0.34% overall) required early bar removal at 3 and 18 months because of recurring infections. Early bar removal should be a rare morbidity with the Nuss repair.

摘要

目的

手术植入物面临的一大难题是感染。我们对18年期间863例漏斗胸患者行努氏修复术后的各种感染并发症进行了评估。

方法

经机构审查委员会批准,对前瞻性收集的漏斗胸微创修复且发生感染患者的数据库进行回顾性分析。所有患者术前均接受静脉抗生素治疗,持续至出院。术后持续发热的患者出院时带口服抗生素。

结果

从1987年1月至2005年9月,863例患者接受了漏斗胸微创修复,13例(1.5%)发生术后感染。其中包括6例钢板感染、4例蜂窝织炎和3例缝线脓肿。蜂窝织炎定义为红斑和皮温升高,对抗生素单疗程治疗有效。钢板感染定义为与钢板接触处的脓肿。手术引流和长期抗生素治疗使其中3例脓肿得到解决,而3例患者需要早期取出钢板(1例在3个月后,2例在18个月后)。培养结果在每例中均鉴定出单一病原体,金黄色葡萄球菌是最常见的病原体(83%),且均对甲氧西林敏感。如果放置了稳定器,所有感染均发生在稳定器一侧。

结论

努氏修复术后感染并发症并不常见,在我们的患者中发生率为1.5%。已发表的术后感染率为1.0%至6.8%。浅表感染仅用抗生素即可治愈。钢板感染仅发生0.7%,需要手术引流和长期抗生素治疗。其中仅3例(钢板感染的50%,总体的0.34%)因反复感染在3个月和18个月时需要早期取出钢板。对于努氏修复术,早期取出钢板应是一种罕见的并发症。

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