Zima V L, Sushko L A, Stepankovskaia G K, Kurskiĭ M D
Ukr Biokhim Zh. 1977 Mar-Apr;49(2):83-7.
A comparative study was performed for actomyosin complexes of the female rabbit myometrium in the state of labour (actomyosin of the control) and secondary uterine inertia (actomyosin of the model). Under the secondary uterine inertia the activity of actomyosin Ca2+- and Mg2+-ATPase decreases. When pH of the medium changes, ATPase of control actomyosin has two peaks of the activity: at rH 6.0 and pH 9.0, that of the model at pH 6.0. Actomyosin of the model and control differs by a degree and rate of superprecipitation, thermal stability and structure. It is supposed that the structural changes in actomyosin under the secondary uterine inertia occur due to accumulation of the metabolism products, the level of which with this pathology is beyond the limits of the adaptation potentialities of the organism.
对处于分娩状态的雌性兔子宫肌层的肌动球蛋白复合物（对照的肌动球蛋白）和继发性子宫收缩乏力（模型的肌动球蛋白）进行了一项比较研究。在继发性子宫收缩乏力的情况下，肌动球蛋白Ca2 + -和Mg2 + -ATP酶的活性降低。当培养基的pH值变化时，对照肌动球蛋白的ATP酶有两个活性峰值：在pH 6.0和pH 9.0时，模型的ATP酶在pH 6.0时有活性峰值。模型和对照的肌动球蛋白在超沉淀程度和速率、热稳定性和结构方面存在差异。据推测，继发性子宫收缩乏力时肌动球蛋白的结构变化是由于代谢产物的积累所致，在这种病理状态下，代谢产物的水平超出了机体适应潜力的限度。
