Funayama Emi, Igawa Hiroharu H, Nishizawa Noriko, Oyama Akihiko, Yamamoto Yuhei
Department of Plastic and Reconstructive Surgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Otolaryngol Head Neck Surg. 2007 Jan;136(1):33-7. doi: 10.1016/j.otohns.2006.08.020.
To investigate the incidence of unilateral hypodynamic palate (UHP) and velopharyngeal insufficiency (VPI) in hemifacial microsomia (HFM), and to determine the dysmorphic manifestations having significant associations with UHP/VPI in HFM.
This was a nonrandomized study of 48 patients with unilateral HFM without cleft palate. The correlation between each anomaly and UHP/VPI was analyzed statistically. In addition, we observed 4 HFM patients with cleft palate to examine the influence on cleft palate speech.
The incidence of UHP in HFM was 50.0% and that of VPI was 14.6%. All the VPI patients had UHP. Severe micrognathia and soft tissue deficiency, macrostomia, and mental retardation were significant risk factors for developing VPI in HFM. Moreover, UHP exacerbated speech in HFM with cleft lip and palate.
Significant correlations were detected between VPI and HFM. This finding should be helpful in the overall management of HFM.
探讨半侧颜面短小畸形（HFM）中单侧动力不足性腭（UHP）及腭咽闭合不全（VPI）的发生率，并确定HFM中与UHP/VPI有显著关联的畸形表现。
这是一项对48例无腭裂的单侧HFM患者进行的非随机研究。对每种异常与UHP/VPI之间的相关性进行统计学分析。此外，我们观察了4例有腭裂的HFM患者，以研究其对腭裂语音的影响。
HFM中UHP的发生率为50.0%，VPI的发生率为14.6%。所有VPI患者均有UHP。严重小下颌及软组织缺损、大口畸形和智力发育迟缓是HFM中发生VPI的显著危险因素。此外，UHP会加重唇腭裂型HFM的语音问题。
检测到VPI与HFM之间存在显著相关性。这一发现应有助于HFM的整体管理。
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