University of Wyoming, Laramie, WY, USA.
University of Washington School of Medicine, Seattle, WA, USA.
Cleft Palate Craniofac J. 2024 Nov;61(11):1803-1813. doi: 10.1177/10556656231183776. Epub 2023 Jun 25.
To quantify differences in levator veli palatini (LVP) muscle dimensions based on age, sex, and race and determine the typical range of asymmetry between the left and right sides of the LVP under age 2.
Retrospective cohort study.
Children's tertiary care hospital.
A retrospective chart review of non-cleft patients under 2 who received a volumetric FLAIR MRI sequence within the past 18 months identified 216 patient scans. Exclusion criteria left 200 scans for analysis. Measurements of the LVP were obtained consistent with previous literature.
Corrected age, sex, and race.
MAIN OUTCOME MEASURE(S): LVP muscle dimensions.
A significant (< .0001) difference between corrected age groups based on the overall combination of LVP variables after controlling for sex and race. Significant age differences included average extravelar length ( < .0001), average intravelar length ( < .0001), midline thickness ( < .0001), and average ( < .0001) and difference ( = .0413) in insertion thickness. Significant sex differences included average intravelar length ( = .0412) and average insertion thickness ( = .0281). Significant race differences included average insertion thickness ( = .0334) and difference in intravelar length ( = .0473). Differences between left and right total length ( = .0491) and angle of origin ( < .0001) were significant.
Differences in LVP morphology were observed in individuals under 2 years or age related to age, sex, and race. While asymmetry was significant in some dimensions, it varied by age range.
基于年龄、性别和种族量化腭帆提肌(LVP)肌肉尺寸的差异,并确定 2 岁以下 LVP 左右两侧不对称的典型范围。
回顾性队列研究。
儿童三级护理医院。
对过去 18 个月内接受过容积 FLAIR MRI 序列的 2 岁以下非腭裂患者进行回顾性图表审查,确定了 216 名患者的扫描。排除标准留下 200 个扫描进行分析。LVP 的测量符合先前的文献。
校正年龄、性别和种族。
LVP 肌肉尺寸。
在控制性别和种族后,基于 LVP 变量的整体组合,校正年龄组之间存在显著差异(<0.0001)。年龄差异显著,包括平均外帆长度(<0.0001)、平均内帆长度(<0.0001)、中线厚度(<0.0001)以及平均(<0.0001)和插入厚度差异(=0.0413)。性别差异显著,包括平均内帆长度(=0.0412)和平均插入厚度(=0.0281)。种族差异显著,包括平均插入厚度(=0.0334)和内帆长度差异(=0.0473)。左、右总长度(=0.0491)和起源角度差异(<0.0001)显著。
在 2 岁以下或与年龄相关的个体中观察到 LVP 形态存在差异,与年龄、性别和种族有关。虽然某些维度的不对称性显著,但它因年龄范围而异。