Yau Franklin S, Rosero Eric B, Clagett G Patrick, Valentine R James, Modrall Gregory J, Arko Frank R, Timaran Carlos H
Division of Vascular and Endovascular Surgery, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390-9157, USA.
J Vasc Surg. 2007 Jan;45(1):96-100. doi: 10.1016/j.jvs.2006.08.087.
Small abdominal aortic aneurysms (AAAs; 4-5.4 cm) are more likely to be suitable for endovascular aneurysm repair (EVAR) than large aortic aneurysms (>5.5 cm). The purpose of this study was to determine whether small AAA growth is associated with the development of morphologic characteristics that decrease eligibility for EVAR.
We studied 54 patients who underwent 2 or more computed tomography scans with 3-dimensional reconstruction during surveillance of small AAAs. Morphologic aortic aneurysm features and changes were measured according to Society for Vascular Surgery reporting standards. Suitability for EVAR was determined by neck anatomy (diameter, length, and angulations), iliac artery morphology, and total aortic aneurysm angulation and tortuosity.
The median age of the study cohort was 73 years (interquartile range [IQR], 65-77 years). The median follow-up period was 24 months (IQR, 15-36 months). The median small AAA diameter increased from 44.5 mm (IQR, 41-48 mm) to 48.9 mm (IQR, 45.7-52.0 mm). The median aortic neck diameter increased from 23.0 to 24.0 mm (P = .002), whereas median neck length decreased from 26.5 to 20.0 mm (P = .001). Aortic aneurysm median tortuosity index increased from 1.09 to 1.11 (P = .05). No significant changes in iliac artery morphology occurred. Overall, the anatomic suitability for endovascular repair did not significantly change during the study period (74% vs 69%; McNemar test; P = .25).
Changes in aortic morphology are frequently associated with small AAA growth at mid-term follow-up, but such changes are minor and do not affect overall anatomic suitability for EVAR. These data reveal that continued surveillance of small AAAs does not threaten the window of opportunity for EVAR.
与大的腹主动脉瘤(>5.5 cm)相比,小的腹主动脉瘤(4 - 5.4 cm)更有可能适合进行血管腔内动脉瘤修复术(EVAR)。本研究的目的是确定小的腹主动脉瘤生长是否与降低EVAR适用性的形态学特征的发展相关。
我们研究了54例在小腹主动脉瘤监测期间接受2次或更多次三维重建计算机断层扫描的患者。根据血管外科学会报告标准测量腹主动脉瘤的形态特征和变化。通过颈部解剖结构(直径、长度和角度)、髂动脉形态以及腹主动脉瘤的总角度和迂曲度来确定EVAR的适用性。
研究队列的中位年龄为73岁(四分位间距[IQR],65 - 77岁)。中位随访期为24个月(IQR,15 - 36个月)。小腹主动脉瘤的中位直径从44.5 mm(IQR,41 - 48 mm)增加到48.9 mm(IQR,45.7 - 52.0 mm)。主动脉颈部的中位直径从23.0增加到24.0 mm(P = 0.00),而颈部中位长度从26.5减少到20.0 mm(P = 0.001)。腹主动脉瘤的中位迂曲指数从1.09增加到1.11(P = 0.05)。髂动脉形态无显著变化。总体而言,在研究期间血管腔内修复的解剖学适用性没有显著变化(74%对69%;McNemar检验;P = 0.25)。
在中期随访中,主动脉形态的变化常与小腹主动脉瘤的生长相关,但这些变化较小,不影响EVAR的总体解剖学适用性。这些数据表明,对小腹主动脉瘤的持续监测不会威胁到EVAR的机会窗口。