Leiberman J, Chaim W, Cohen A, Czernobilsky B
Br J Obstet Gynaecol. 1975 Nov;82(11):917-21. doi: 10.1111/j.1471-0528.1975.tb00598.x.
Curettings from a 42-year-old woman who suffered from heartburn, weight loss and irregular vaginal bleeding showed apparently metastatic mucoid adenocarcinoma in the endocervix. The primary site of tumour was not evident. At laparotomy a gastric adenocarcinoma was found and total hysterectomy with bilateral salpingo-oophorectomy and partial gastrectomy were performed. Histological examination showed a diffuse mucoid adenocarcinoma of stomach with metastases to lymph nodes, uterine body, cervix and one ovary. The literature about metastasis of extragenital cancer to the uterus is reviewed and possible mechanisms are discussed.
一位42岁女性,有烧心、体重减轻和不规则阴道出血症状,其宫颈刮出物显示宫颈内膜有明显转移性黏液腺癌。肿瘤原发部位不明确。剖腹探查时发现胃腺癌,遂行全子宫切除术、双侧输卵管卵巢切除术和部分胃切除术。组织学检查显示胃弥漫性黏液腺癌,伴有淋巴结、子宫体、宫颈和一侧卵巢转移。本文回顾了关于生殖器外癌症转移至子宫的文献,并探讨了可能的机制。