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A randomized trial of primary liver transplantation under immunosuppression with FK 506 vs cyclosporine.

作者信息

Fung J, Abu-Elmagd K, Jain A, Gordon R, Tzakis A, Todo S, Takaya S, Alessiani M, Demetris A, Bronster O

机构信息

Dept. of Surgery, University of Pittsburgh School of Medicine, Pennsylvania 15213.

出版信息

Transplant Proc. 1991 Dec;23(6):2977-83.

PMID:1721333
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2950613/
Abstract
摘要

相似文献

1
A randomized trial of primary liver transplantation under immunosuppression with FK 506 vs cyclosporine.一项关于在免疫抑制下使用FK 506与环孢素进行原位肝移植的随机试验。
Transplant Proc. 1991 Dec;23(6):2977-83.
2
FK 506 versus cyclosporine in pediatric liver transplantation.儿童肝移植中FK506与环孢素的比较
Transplant Proc. 1991 Dec;23(6):3010-5.
3
Comparison of FK 506- and cyclosporine-based immunosuppression: FK 506 therapy significantly reduces the incidence of acute, steroid-resistant, refractory, and chronic rejection whilst possessing a comparable safety profile. European FK 506 Multicenter Liver Study Group.
Transplant Proc. 1995 Feb;27(1):45-9.
4
A comparison of tacrolimus (FK 506) and cyclosporine for immunosuppression in liver transplantation.他克莫司（FK 506）与环孢素在肝移植免疫抑制中的比较。
N Engl J Med. 1994 Oct 27;331(17):1110-5. doi: 10.1056/NEJM199410273311702.
5
The superior immunosuppressant according to diagnosis: FK 506 or cyclosporine A.根据诊断结果使用的最佳免疫抑制剂：FK506或环孢素A。
Transplant Proc. 1995 Feb;27(1):1117-20.
6
Tacrolimus (FK 506) therapy is associated with a significant reduction in immunosuppressive treatment failures following primary liver transplantation.
Transplant Proc. 1996 Apr;28(2):1008-10.
7
The spectrum of aspergillosis in liver transplant patients: comparison of FK 506 and cyclosporine immunosuppression.肝移植患者曲霉病的谱：FK 506与环孢素免疫抑制的比较
Transplant Proc. 1991 Dec;23(6):3040-1.
8
Long-term comparison of tacrolimus versus cyclosporine in liver transplantation. The US FK Study Group.他克莫司与环孢素在肝移植中的长期比较。美国FK研究小组。
Transplant Proc. 1998 Jun;30(4):1399-400. doi: 10.1016/s0041-1345(98)00288-7.
9
Randomized trial in primary liver transplantation under immunosuppression with FK 506 or cyclosporine.在使用FK 506或环孢素进行免疫抑制的原位肝移植中的随机试验。
Transplant Proc. 1993 Feb;25(1 Pt 2):1130.
10
[Comparison between tacrolimus (FK 506) and cyclosporin in immunosuppressive therapy after liver transplantation].[肝移植后免疫抑制治疗中他克莫司（FK 506）与环孢素的比较]
Z Gastroenterol. 1995 Oct;33(10):624-5.

引用本文的文献

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Long-term Follow-up of a Randomized Trial of Tacrolimus or Cyclosporine A Microemulsion in Children Post Liver Transplantation.他克莫司或环孢素A微乳剂在儿童肝移植术后的随机试验长期随访
Transplant Direct. 2021 Sep 20;7(10):e765. doi: 10.1097/TXD.0000000000001221. eCollection 2021 Oct.
2
Maintenance immunosuppression for adults undergoing liver transplantation: a network meta-analysis.肝移植成年受者的维持性免疫抑制：一项网状Meta分析。
Cochrane Database Syst Rev. 2017 Mar 31;3(3):CD011639. doi: 10.1002/14651858.CD011639.pub2.
3
Coronary Computed Tomography Angiography in Combination with Coronary Artery Calcium Scoring for the Preoperative Cardiac Evaluation of Liver Transplant Recipients.冠状动脉计算机断层扫描血管造影结合冠状动脉钙化评分用于肝移植受者术前心脏评估
Biomed Res Int. 2017;2017:4081525. doi: 10.1155/2017/4081525. Epub 2017 Jan 10.
4
A prospective, randomized trial of complete avoidance of steroids in liver transplantation with follow-up of over 7 years.一项前瞻性、随机临床试验，在肝移植中完全避免使用类固醇，随访时间超过 7 年。
HPB (Oxford). 2013 Apr;15(4):286-93. doi: 10.1111/j.1477-2574.2012.00576.x. Epub 2012 Sep 28.
5
Immunosuppression strategies after liver transplantation: a single centre experience in 57 liver transplant recipients.肝移植后的免疫抑制策略：57例肝移植受者的单中心经验
Indian J Surg. 2007 Oct;69(5):187-90. doi: 10.1007/s12262-007-0018-0. Epub 2008 Jul 30.
6
Phase II study of tacrolimus and methotrexate for prophylaxis of acute graft-versus-host disease after HLA-A, B, and DRB1 genotypically mismatched unrelated bone marrow transplantation among Japanese patients.他克莫司与甲氨蝶呤预防日本患者 HLA - A、B 和 DRB1 基因配型不合的非亲缘骨髓移植后急性移植物抗宿主病的 II 期研究。
Int J Hematol. 2009 Jan;89(1):98-105. doi: 10.1007/s12185-008-0219-8. Epub 2008 Dec 4.
7
Cyclosporin versus tacrolimus for liver transplanted patients.肝移植患者使用环孢素与他克莫司的比较。
Cochrane Database Syst Rev. 2006 Oct 18;2006(4):CD005161. doi: 10.1002/14651858.CD005161.pub2.
8
Immunosuppressive drugs in paediatric liver transplantation.儿童肝移植中的免疫抑制药物
Paediatr Drugs. 2001;3(1):43-60. doi: 10.2165/00128072-200103010-00004.
9
Hepatic and intestinal transplantation at the University of Pittsburgh.匹兹堡大学的肝脏和肠道移植
Clin Transpl. 1998:263-86.
10
Vasorelaxation and inhibition of the voltage-operated Ca2+ channels by FK506 in the porcine coronary artery.FK506对猪冠状动脉的血管舒张作用及对电压门控性Ca2+通道的抑制作用
Br J Pharmacol. 1999 Feb;126(3):717-29. doi: 10.1038/sj.bjp.0702339.

本文引用的文献

1
Effect of a new immunosuppressive agent, FK 506, on heterotopic cardiac allotransplantation in the rat.新型免疫抑制剂FK 506对大鼠异位心脏同种异体移植的影响。
Transplant Proc. 1987 Feb;19(1 Pt 2):1284-6.
2
FK 506 for liver, kidney, and pancreas transplantation.用于肝脏、肾脏和胰腺移植的FK 506。
Lancet. 1989 Oct 28;2(8670):1000-4. doi: 10.1016/s0140-6736(89)91014-3.
3
A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase.免疫抑制剂FK506的一种受体是一种顺反肽基脯氨酰异构酶。
Nature. 1989 Oct 26;341(6244):758-60. doi: 10.1038/341758a0.
4
A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin.免疫抑制剂FK506的一种胞质结合蛋白具有肽基脯氨酰异构酶活性，但与亲环蛋白不同。
Nature. 1989 Oct 26;341(6244):755-7. doi: 10.1038/341755a0.
5
FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro.FK-506，一种从链霉菌中分离出的新型免疫抑制剂。II. FK-506的体外免疫抑制作用。
J Antibiot (Tokyo). 1987 Sep;40(9):1256-65. doi: 10.7164/antibiotics.40.1256.
6
Immunosuppressive effect of FK-506 on in vitro lymphocyte alloactivation: synergism with cyclosporine A.FK-506对体外淋巴细胞同种异体激活的免疫抑制作用：与环孢素A的协同作用。
Transplant Proc. 1987 Oct;19(5 Suppl 6):40-4.
7
A highly sensitive method to assay FK-506 levels in plasma.一种检测血浆中FK-506水平的高灵敏度方法。
Transplant Proc. 1987 Oct;19(5 Suppl 6):23-9.
8
Synexin: a target protein for toxic effects of cyclosporine and FK 506 in endocrine cells.联会蛋白：环孢素和FK506在内分泌细胞中毒性作用的靶蛋白。
Transplant Proc. 1991 Dec;23(6):3166-8.
9
Posttransplant lymphoproliferative disorders occurring under primary FK 506 immunosuppression.在原发性FK 506免疫抑制下发生的移植后淋巴细胞增生性疾病。
Transplant Proc. 1991 Dec;23(6):3044-6.
10
Effects of in vivo treatment with FK506 on natural killer cells in rats.FK506体内治疗对大鼠自然杀伤细胞的影响。
Transplantation. 1991 Apr;51(4):913-5. doi: 10.1097/00007890-199104000-00037.