Eurenius Eva, Brodin Nina, Lindblad Staffan, Opava Christina H
Rehabcentrum, Skellefteå Hospital, Skellefteå, Sweden.
J Rheumatol. 2007 Jan;34(1):10-5.
To describe changes over one year in physical activity, body functions, and disease activity in patients with rheumatoid arthritis (RA) and to identify predictors for physical activity and general health perception.
One hundred two patients with RA were recruited for the study (median age 57 yrs, range 19-84; median disease duration 15 mo, range 4-78; 76% women). Self-reported data on physical activity and health locus of control, tests of lower extremity function, grip force, joint range of motion, balance, and measures of disease activity, including pain, general health perception, Health Assessment Questionnaire (HAQ), and Disease Activity Score (DAS28), were collected on 2 occasions, one year apart. Each variable was dichotomized to fit logistic regression models, performed to identify which variables predicted physical activity and general health perception over one year.
Physical activity was stable, while lower extremity function, grip force, and range of motion improved and DAS28 decreased significantly over one year. A high physical activity level at baseline was the only predictor of high physical activity (odds ratio 3.85, 95% confidence interval 1.67-9.09) one year later. Low pain (OR 8.47, 95% CI 2.97-24.39), high physical activity (OR 3.72, 95% CI 1.39-10.10), and good lower extremity function (OR 2.94, 95% CI 1.04-8.33) were identified as predictors of good general health perception.
While pain is a well known predictor of general health perception, to our knowledge, this is the first study to identify predictive factors related to physical activity and lower extremity function as important for perceived health among patients with RA.
描述类风湿关节炎(RA)患者一年中身体活动、身体功能和疾病活动的变化,并确定身体活动和总体健康感知的预测因素。
招募了102例RA患者进行研究(中位年龄57岁,范围19 - 84岁;中位病程15个月,范围4 - 78个月;76%为女性)。在相隔一年的两个时间点收集关于身体活动和健康控制点的自我报告数据、下肢功能测试、握力、关节活动范围、平衡以及疾病活动指标,包括疼痛、总体健康感知、健康评估问卷(HAQ)和疾病活动评分(DAS28)。将每个变量进行二分法处理以适应逻辑回归模型,通过该模型确定哪些变量可预测一年中的身体活动和总体健康感知。
身体活动保持稳定,而一年中下肢功能、握力和活动范围有所改善,DAS28显著下降。基线时较高的身体活动水平是一年后高身体活动水平的唯一预测因素(比值比3.85,95%置信区间1.67 - 9.09)。低疼痛(比值比8.47,95%置信区间2.97 - 24.39)、高身体活动(比值比3.72,95%置信区间1.39 - 10.10)和良好的下肢功能(比值比2.94,95%置信区间1.04 - 8.33)被确定为良好总体健康感知的预测因素。
虽然疼痛是总体健康感知的一个众所周知的预测因素,但据我们所知,这是第一项确定与身体活动和下肢功能相关的预测因素对RA患者的感知健康很重要的研究。