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[眼角膜传入神经末梢中介质受体的相互关系]

[Interrelationship of the mediator receptors in the terminals of the afferent nerves of the cornea of the eye].

作者信息

Sliusar' N G, Kudrin A N

出版信息

Biull Eksp Biol Med. 1975 Apr;79(4):16-8.

PMID:172168
Abstract

In local application of substances with a mediator action (adrenaline, acetylcholine, histamine) and blockers of specific receptors (dihydroergotoxin, inderal, atropine and of subcutaneous dimedrol) together with dicaine it was possible to reveal a distinct presence in the cornea of the eye of the mediator receptors capable of influencing one another. Pharmacological analysis permitted a supposition to be made that there were two receptor systems in the sensory nerve endings of the cornea; these systems were in reciprocal inhibitory relations; due to this their regular influence on the processes of excitation and inhibition is effected in the sensory nerve ending.

摘要

在局部应用具有介质作用的物质(肾上腺素、乙酰胆碱、组胺)以及特异性受体阻滞剂(双氢麦角毒碱、心得安、阿托品和皮下注射苯海拉明)并同时使用地卡因时,有可能揭示出在眼的角膜中存在着能够相互影响的介质受体。药理学分析使得可以推测在角膜的感觉神经末梢中有两个受体系统;这些系统处于相互抑制关系;正因为如此,它们对感觉神经末梢中的兴奋和抑制过程产生规律性影响。

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