TRPM3.
作者信息
Oberwinkler J, Phillipp S E
机构信息
Institut für klinische und experimentelle Pharmakologie und Toxikologie der Universität des Saarlandes, 66421 Homburg, Germany.
出版信息
Handb Exp Pharmacol. 2007(179):253-67. doi: 10.1007/978-3-540-34891-7_15.
PMID:17217062
Abstract
TRPM3 is the last identified member of the TRPM subfamily and is most closely related to TRPM1. Due to alternative splicing, the TRPM3 gene encodes a large number of different variants. One splice event, affecting the pore-forming region of the channel, changes its selectivity for divalent cations. In this review, we give an overview of the identified TRPM3 variants and compare their functional properties.
摘要
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