双锥酰胺A的全合成。
Total synthesis of bistramide A.
作者信息
Lowe Jason T, Wrona Iwona E, Panek James S
机构信息
Department of Chemistry and Center for Chemical Methodology and Library Development, Metcalf Center for Science and Engineering, Boston University, 590 Commonwealth Avenue, Boston, Massachusetts 02215, USA.
出版信息
Org Lett. 2007 Jan 18;9(2):327-30. doi: 10.1021/ol062957y.
PMID:17217296
Abstract
An asymmetric synthesis of the marine metabolite bistramide A is reported. The synthesis relies on the utility of three different organosilane reagents to construct all principle fragments and 8 of the 11 stereogenic centers of the natural product. [structure: see text].
摘要
报道了海洋代谢产物双瑞香酰胺A的不对称合成。该合成依赖于三种不同有机硅烷试剂的作用来构建天然产物的所有主要片段以及11个手性中心中的8个。[结构：见原文]
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