Lu Xin, Mao Yi-lei, Sang Xin-ting, Yang Zhi-ying, Zhong Shou-xian, Huang Jie-fu
Department of Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Zhonghua Wai Ke Za Zhi. 2006 Oct 1;44(19):1327-9.
To investigate the feasibility and safety of one-day bowel preparation for colorectal surgery.
Forty patients undergone colorectal surgery were divided randomly into the Control group and the Experimental group and received 3-day magnesium sulfate and 1-day sodium phosphate bowel preparations before the operation, respectively. The levels of hemoglobin, hematocrit, serum electrolytes, and anaerobe counts in the stool prior and post bowel preparation were examined. The general status, surgical complications, and structure of intestinal mucosa in the patients were observed after the operation.
There was no significant difference in the anastomoses healing, infectious complications, serum tests and intestinal mucosa structures between the two groups. Less diarrhea occurred prior and post the surgery in the experimental group, and they felt better with the bowel preparation. The anaerobe counts in stool were higher after the bowel preparation than before in both groups.
One-day bowel preparation with sodium phosphate is a safe and reliable method for colorectal surgery. The shortening of preparation time can reduce the degrees of uncomfortable feeling and disruptions of intestinal micro-ecology and barrier.
探讨结直肠手术一日肠道准备的可行性及安全性。
将40例行结直肠手术的患者随机分为对照组和试验组，分别于术前给予3日硫酸镁肠道准备和1日磷酸钠肠道准备。检测肠道准备前后的血红蛋白、血细胞比容、血清电解质水平及粪便厌氧菌计数。术后观察患者的一般状况、手术并发症及肠黏膜结构。
两组在吻合口愈合、感染并发症、血清检查及肠黏膜结构方面无显著差异。试验组手术前后腹泻较少，且对肠道准备的接受度更好。两组肠道准备后粪便厌氧菌计数均高于准备前。
磷酸钠一日肠道准备是结直肠手术安全可靠的方法。准备时间的缩短可减轻不适程度，减少肠道微生态及屏障的破坏。
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