Meeuwis C, Peters N H G M, Mali W P Th M, Gallardo A M Fernandez, van Hillegersberg R, Schipper M E I, van den Bosch M A A J
Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, E.01.132, 3584 CX Utrecht, The Netherlands.
Eur J Radiol. 2007 May;62(2):283-8. doi: 10.1016/j.ejrad.2006.12.006. Epub 2007 Jan 10.
To report the accuracy of magnetic resonance imaging (MRI)-guided needle localization for diagnosis of MRI detected suspicious breast lesions located in difficult accessible regions of the breast, using the freehand method in a 3.0 T closed bore magnet.
In five patients with five MRI-only breast lesions underwent MRI-guided needle localization for histopathologic evaluation of the lesions. All interventional procedures were performed in a 3.0 T MRI system with the patient in prone position and by using a dedicated phased array breast coil. MRI-guided needle localizations were performed by using a freehand technique. In our study, the high-resolution scan allowed preprocedural localization of all lesions without use of contrast enhancement. In all cases contrast-enhanced MRI was performed after insertion of the wire to confirm the tip of the wire in direct contact with the enhancing lesion.
Needle localizations were performed in five patients. Histopathologic evaluation of tissue after surgery excision biopsy revealed one lymph node, three invasive ductal carcinoma and one ductal carcinoma in situ. Lesion size varied from 6 to 30 mm. Mean duration time was 25 min. No complications occurred during the intervention method. In the patient with the benign lesion control MRI of the breast after 6 months confirmed lesion removal.
MRI-guided needle localization by using a freehand technique in a 3.0 T closed bore magnet is a safe and accurate method for diagnosis of difficult accessible breast lesions only visible on MRI.
报告在3.0 T 封闭孔径磁体中使用徒手技术进行磁共振成像（MRI）引导下针定位，以诊断位于乳房难以触及区域的MRI检测到的可疑乳房病变的准确性。
对5例仅通过MRI发现乳房病变的患者进行MRI引导下针定位，以对病变进行组织病理学评估。所有介入操作均在3.0 T MRI系统中进行，患者取俯卧位，使用专用相控阵乳房线圈。MRI引导下针定位采用徒手技术。在我们的研究中，高分辨率扫描允许在不使用对比增强的情况下对所有病变进行术前定位。在所有病例中，插入导丝后进行对比增强MRI，以确认导丝尖端与强化病变直接接触。
对5例患者进行了针定位。手术切除活检后组织的组织病理学评估显示1个淋巴结、3例浸润性导管癌和1例导管原位癌。病变大小从6到30 mm不等。平均持续时间为25分钟。介入过程中未发生并发症。在患有良性病变的患者中，6个月后乳房的对照MRI证实病变已切除。
在3.0 T封闭孔径磁体中使用徒手技术进行MRI引导下针定位是一种安全、准确的方法，可用于诊断仅在MRI上可见的难以触及的乳房病变。
