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Synthesis of the isonicotinoylnicotinamide scaffolds of the naturally occurring isoniazid-NAD(P) adducts.

作者信息

Delaine Tamara, Bernardes-Génisson Vania, Meunier Bernard, Bernadou Jean

机构信息

Laboratoire de Chimie de Coordination du CNRS, 205 route de Narbonne, 31077 Toulouse cedex 4, France.

出版信息

J Org Chem. 2007 Jan 19;72(2):675-8. doi: 10.1021/jo062100e.

DOI:10.1021/jo062100e
PMID:17221997
Abstract

The first syntheses of the 1-hydroxy-1-(pyridin-4-yl)-1,2-dihydro-3H-pyrrolo[3,4-c]pyridin-3-one heterocycle and the 3-aminocarbonyl-4-isonicotinoyl-1,4-dihydropyridine framework present in the isoniazid-NAD(P) adducts are described.

摘要

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